摘要
目的监测肇庆市结核病防治所收治的结核病患者对抗结核药物不良反应(ADR)发生的规律及特点,为临床安全用药提供依据。方法对500名初诊结核病患者进行为期1年的前瞻性监测研究。分析ADR的规律及特点。结果出现不良反应共46例。其中居前三位的不良反应是:消化系统不良反应17例、泌尿系统不良反应10例及过敏反应6例。结论加强抗结核药物不良反应监测,可避免或减少ADR的发生,指导临床安全用药。
Aim To monitor features of adverse drug reactions occurred to those treated with anti-tuberculous drug （ADR） and Offer scientific basis for safely use of the drugs. Methods The prospective monitoring study was performed on 500 firstly diagnosed tuberculous patientsr for a period of one year. Adverse drug reactions occurred to 46 eases and the three top adverse reactions were digestive system （occurred to 17 cases）,urinary sesterm （occurred to 10 eases） and anaphylaxis（oceurred to 6 eases）. Conclusion The work of monitoring of adverse drug reactions be strengthened to avoid or reduce the occurrence of adverse reactions to antituberculous drugs and provide reference for clinical use of the drugs
出处
《中国热带医学》
CAS
2010年第5期542-543,共2页
China Tropical Medicine
基金
广东省肇庆市2009年度科研立项(编号:2009E2817)
关键词
抗结核药
不良反应
前瞻性研究
Anti-tuberculous drag
Adverse drug reactions
Prospective study
