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检测血清半乳甘露聚糖对肾移植术后侵袭性肺曲霉病的诊断价值 被引量：1

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摘要 目的探讨检测血清曲霉半乳甘露聚糖(GM)抗原对肾移植术后侵袭性肺曲霉病的诊断价值。方法对31例肾移植术后合并肺部感染且对广谱抗生素治疗效果不佳的患者,每周采集血液标本2次进行GM试验,共测定标本92份。GM检测采用双夹心酶联免疫吸附法。对GM试验阳性的患者给予伊曲康唑或伏立康唑抢先抗曲霉治疗。结果31例患者中11例GM试验阳性(35.5%)。GM阳性的11例中,7例确诊为侵袭性肺曲霉病。9例GM试验阳性的患者完成针对曲霉病的抢先治疗,7例有效,2例无效死亡。结论检测血清GM抗原可作为早期诊断肾移植术后侵袭性肺曲霉病的一种有效方法。
作者 万志辉 金丹
机构地区 武汉大学人民医院呼吸科 湖北中医学院医学检验与技术学院
出处 《湖北中医学院学报》 2010年第2期54-55,共2页 Journal of Hubei College of Traditional Chinese Medicine
关键词 曲霉病 肺 肾移植 血清半乳甘露聚糖 诊断
分类号 R446.11 [医药卫生—诊断学]
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参考文献5

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共引文献423

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湖北中医学院学报
2010年 第2期

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