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胸腺肽α_1在慢性病毒性肝炎抗病毒治疗中的应用 被引量:16

Application of thymosin α_1 in the antiviral treatment of chronic viral hepatitis
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摘要 胸腺肽α1是从胸腺素第5组分中分离纯化出的一种小分子生物活性多肽。近年来,胸腺肽α1开始用于慢性乙型病毒性肝炎和慢性丙型病毒性肝炎的治疗,其耐受性较好,可能成为一种较好的治疗药物。但是,由于胸腺肽α1治疗肝炎相关数据的缺乏,使得人们对其治疗作用及作用机制还不太明确。鉴于此,本文对胸腺肽α1在病毒性肝炎抗病毒治疗中的应用进行综述。 Thymosin α1 is a small molecule bioactive peptide which isolated from thymosin fraction 5.In recent years,thymosin α1 has begun to be used in treating chronic viral hepatitis B and chronic viral hepatitis C.As shown by the outcome of a better tolerance,thymosin α1 may become a better drug in treating viral hepatitis with wide range of clinical applications.However,due to lack of data of thymosin α1 in clinical treatment,its therapeutic effect and mechanism are still not very clear.The article reviewed recent applications of thymosin α1 in treating viral hepatitis.
作者 张久聪 孙利
出处 《实用药物与临床》 CAS 2010年第2期135-137,共3页 Practical Pharmacy and Clinical Remedies
关键词 胸腺肽Α1 慢性乙型肝炎 慢性丙型肝炎 Thymosin α1 Chronic viral hepatitis B Chronic viral hepatitis C
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参考文献20

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二级参考文献20

  • 1聂青和,张久聪,闫英琪.胸腺素α1治疗慢性丙型肝炎的临床荟萃分析[J].实用肝脏病杂志,2005,8(6):346-351. 被引量:7
  • 2聂青和,张久聪.胸腺肽α_1单用治疗慢性乙型肝炎的临床荟萃分析[J].中国实用内科杂志,2006,26(3):382-386. 被引量:19
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