摘要
目的:研究五灵脂石油醚部分的化学成分。方法:乙醇热回流提取五灵脂药材,提取液浓缩后拌硅胶经硅胶柱色谱,依次用石油醚、乙酸乙酯、正丁醇洗脱,回收溶剂得石油醚、乙酸乙酯、正丁醇部分。用气相色谱-质谱(GC/MS)联用技术对石油醚部分化学成分进行分离鉴定,用面积归一化法确定各成分的相对含量。结果:共鉴定21个化合物,均为首次从五灵脂中分离鉴定出。结论:五灵脂石油醚部分的主要成分为正四十一烷醇(21.72%)、香紫苏醇(14.08%)、棕榈酸(9.11%)等,其中醇类化合物占总量的40%以上。
Objective：To study on the chemical constituents of the petroleum ether extract of Trogopterus xanthippes Milne-Edwards.Method： The ethanol extract of Trogopterus xanthippes Milne-Edwards underwent silica gel chromatography and was eluted by petroleum ether,ethyl acrylate and n-buthanol in turn.The composition of petroleum ether part was analysed and identified by GC /MS and the relative content of composition was calculated by area normalization method.Result： 21 components were identified,and all of them were first discovered from the Excreta of Trogopterus xanthippes Milne-Edwards.Conclusion： Hentetracontan-1-ol（21.72%）,sclareol（14.08%） and n-hexadecanoic acid（9.11%） were the main chemical compositions of the petroleum ether extract,and the content of alcohol components was more than 40% in total.
出处
《中国实验方剂学杂志》
CAS
北大核心
2010年第4期18-20,共3页
Chinese Journal of Experimental Traditional Medical Formulae
基金
国家自然科学基金(30873382)
关键词
五灵脂
化学成分
气相色谱-质谱联用
Trogopterus xanthippes Milne-Edwards
chemical constituents
GC /MS
