摘要
采用克莱森缩合反应合成了６个β－二羰基化合物（Ⅰ），Ⅰ与胍的缩合环化反应等合成了７个取代２－氨基嘧啶（Ⅱ），Ⅱ与２－噻吩磺酰异氰酸酯反应合成了５个含不同取代嘧啶环的２－噻吩磺酰脲（Ⅲ），Ⅱ和Ⅲ中有８个为首次合成，其结构经ＩＲ，１ＨＮＭＲ，元素分析等测试确证，并初步测定了部分化合物的除草活性。
Using Claisen condensation six β dicarbonyl compounds have been synthesized. The compounds reacted with guanidine carbonate to give seven various subatituted 2 aminopyrimidines. Five N′ (substitutedpyrimidin 2 ly) 2 thiophenesulfonylureas are synthesized by nucleophilic addition of 2 aminopyrimidines with 2 thiophenesulfonyl isocyanate. Among them eight were unreported. The structures of substituted 2 aminopyrimidines and their 2 thiophenesulfonylurea derivatives have been confirmed by IR, 1H NMR and elemental analysis,and their herbicidal activities have been tested.
出处
《合成化学》
CAS
CSCD
1998年第4期413-417,共5页
Chinese Journal of Synthetic Chemistry
基金
湖北省自然科学基金
关键词
氨基嘧啶
噻吩磺酰脲
衍生物
除草剂
β Dicarbonyl compounds, 2 Aminopyrimidine, 2 Thiophenesulfonylurea, Synthesis, Herbicidal activity.
