摘要
【目的】分析疣状胃炎（VG）的胃镜和病理表现及与幽门螺杆菌（Hp）感染的关系。【方法】回顾性分析2006年7月1日至2009年7月1日在本院消化内镜室做检查的465例VG患者的胃镜及病理结果。胃镜下观察VG的好发部位、个数、类型，取胃组织做病理检查，尿素酶试验检测HP感染。【结果】VG检出率为3．99％。392例（84．30％）疣状隆起≤10个，73例（15．70％）疣状隆起〉10个；成熟型146例（31．40％），未成熟型319例（68．60％）；单发于胃窦部的最多，为374例（80．60％），其次为同时发生于胃窦和胃角部，为81例（17．46％）；伴随的诊断最多的依次是十二指肠炎65例（13．98％）、消化性溃疡54例（11．61％）、反流性食道炎51例（10．97％）、胃息肉26例（5．59％）。HP阳性者262例（56．34％），HP阴性者203例（43．66％）。232例患者做病理检查，其中肠上皮化生者93例（40．09Yo），异型增生者30例（12．93％），合并萎缩者18例（7．76%）。经统计学分析，成熟型和不成熟型疣状胃炎在肠化、萎缩和异型增生方面差异无显著性（P=0．1925）。【结论】VG多见于胃窦部，不成熟型多见，有相当的Hp感染率及相当的肠上皮化生、异型增生及萎缩比率。但成熟型与不成熟型疣状胃炎在肠化、萎缩和异型增生方面差异无显著性。
[Objective] To analyze gastroscopic and pathologic appearance of verrucosa gastritis（VG） and its relationship to Helicobacter pylori（Hp）. [Methods]A total of 465 cases of VG from July 1st 2006 to July 1st 2009 in digestive endoscopy department of General Air Force Hospital were analyzed retrospectively. The predilection site, number and type under gastroscope were observed. Pathologic examination of gastric tissue was made. Hp infection was detected by urease test. [Results]The detection rate of VG was 3.99%. About 392 cases（84.30%）had 410 verrucosa eminence and 73 cases（15.70%/） had ）10 verrucosa eminence. About 146 cases（31.40%） were mature type and 319（68. 60%） were immature. About 374 cases（80. 60%） were found in gastric antrum and 81（17.46%） were found both in gastric antrum and angularis. The diseases with accompanying diagnosis by turn were duodenitis（65 cases, 13.98%）, peptic ulcer（54 cases, 11.61%）, reflu- xing esophagitis （51 cases, 10.97%） and gastric polyp （26 cases, 5. 590//oo）. Hp infection was positive in 262 cases（56. 34%） and negative in 203 cases（43. 66%）. About 232 cases did pathologic examination. Among them, 93 cases（40.09 % ） were intestinal metaplasia, 30 （ 12.93 % ） were dysplasia, and 18 （7.76 % ） were atrophy. There was no significant difference between mature and immature type in the rate of intestinal metapla- sia, dysplasia, and atrophy（ P ： 0. 1925）. [Conclusion] VG is mostly found in gastric antrum, and most of them is immature type. VG has considerable Hp infection rate and considerable rate of intestinal metaplasia, dysplasia and atrophy. But there is no significant difference between mature and immature type in the rate of intestinal metaplasia, dysplasia, and atrophy.
出处
《医学临床研究》
CAS
2010年第3期478-480,共3页
Journal of Clinical Research
