摘要
【目的】探讨文拉法辛和帕罗西汀对于躯体形式障碍的治疗作用。【方法】对60名躯体形式障碍患者分别用文拉法辛或帕罗西汀治疗8周。采用汉密尔顿抑郁量袁（HAMD）及简明健康测量量表（SF-36）评定药物的疗效。【结果】治疗后两组HAMD评分较治疗前减少，SF-36评分较治疗前提高，差异有显著性（P〈0．01）。8周末文拉法辛组显效率为66．7％，帕罗西汀组显效率为63．3％，两者之间没有显著性差异。【结论】文拉法辛与帕罗西汀对于躯体形式障碍均有治疗作用，两者疗效相当。
[Objective] To explore the efficacy of venlafaxine and paroxetine for the treatment of somatization disorder. [Methods] Sixty patients with somatization disorder were treated with venlafaxine and paroxetine for 8 weeks, respectively. The efficacy was evaluated with Hamilton＇s depression scale（HAMD） and SF-36. [Results] Af- ter treatment, the score of HAMD was lower and SF-36 was higher in venlafaxine group and paroxetine group than that before treatment, and there was significant difference （ P 〈0.01）. At the end of 8th week, effective rates of the venlafaxine group and paroxetine group were 66.7 and 63. 3%, respectively, and there was no significant difference （ P〉0.05）. [Conclusion]The total efficacy of venlafaxine in treating somatization disorder is similar to that of paroxetine.
出处
《医学临床研究》
CAS
2010年第3期453-454,共2页
Journal of Clinical Research
