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多层螺旋CT在冠心病的临床应用价值及存在问题 被引量:14

Clinical applications and pitfalls of Multislice Computed tomography in coronary artery disease
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摘要 目的在病例非选择性的基础上,将多层螺旋CT冠状动脉血管造影(Cq'A)与侵人性冠状动脉造影(ICA)相比,评估其准确性及敏感性,并分析其伪影产生的原因以及解决方法。方法对45名可疑冠心病患者在7~10d先后予以CTA及ICA检查,将二者相比。结果对45名患者从节段水平分析其敏感性、特异性、阳性预测值、阴性预测值为:85.0%,99.1%,93.1%,98.0%;患者水平分别为:84.8%,75.0%,90.3%,64.2%。结论CTA诊断准确性高,尤其表现在节段水平对于阴性预测值判断,从患者水平分析,其诊断价值下降,显示对于高度危险患者,常规行CTA检查,并不能从中获益。由于患者自身或扫描的原因会出现影响图像诊断的伪影,对这些伪影的成因及特点进行分析有助于提高CTA的成功率及避免假阳性的诊断。 Objective Multislice Computed tomography coronary angiography (CTA) is in- creasingly used as an alternative to diagnostic coronary angiography for visualizing coronary arteries. The major limitation of recently published studies, aside from being monocentric in nature and the patients included, is the selection of patients. These studies did not provide any answers for patients who are seen daily in cardiology consultation. The purpose of this study wis to determine the diag- nostic accuracy of CTA as compared with coronary angiography on a population of average patients who were not selected. To investigate the causes and strategies of artifact and pitfalls of coronary artery imaging. Methods Forty- five patients with suspected coronary artery disease underwent CTA followed by invasive coronary angiography 7 with in to 10 days. The diagnostic accuracy de- tection d significant coronary stenoses (greater than 50 % stenoses in arteries greater than 1.5ram in diameter) was determined and the two techniques were compared. Results The sensitivity, specificity, positive and negative predictive value of CTA in detecting significant coronary stenoses were 85.0 %, 99.1%, 93.1% and 98.0 % in per - segment evaluation. During the per - patient evaluation, the efficacy of CTA dropped with the values being 84.8 %, 75.0 %, 90.3 % and 64.2 % re- spectively. Conclusion The use of CTA results in excellent diagnostic accuracy and in anincreased negative predictive value for detecting significant coronary stenoses in per - segment analysis. Perpatient analysis significantly reduced the value of scanning, demonstrating that patients with a high probability of coronary artery disease do not benefit from this type of non - invasive approach. By reasons of patients themselves orscan protocols , the artifacts will appear . To analyze the causes and features of these artifacts will be helpful to elevate the achievement ratio and avoid false positive diagnosis.
作者 洪莉 顾翔
出处 《实用临床医药杂志》 CAS 2010年第3期50-53,共4页 Journal of Clinical Medicine in Practice
关键词 多层螺旋CT冠状动脉血管造影 冠心病 伪影 computed tomography angiograph coronary artery disease artifact
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参考文献11

  • 1Meijboom W B,Meijs M F,Schuijf J D,et al.Diagnostic accuracy of 64-slice computed tomography coronary angiography:a prospective,multicenter,multivendor study[J].J Am Coll Cardiol.2008,Dec 16; 52(25):2135.
  • 2Tan K T,Reed D,Howe J,et al.CT vs conventional angiography in unselected patients with suspected coronary heart disease[J].Int J Cardiol.2007 Sep 14;121(1):125-6.Epub 2006 Nov 22.
  • 3Shabestari A A,Abdi S,Akhlaghpoor S,et al.Diagnostic performance of 64-channel multislice computed tomography in assessment of significant coronary artery disease in symptomatic subjects[J].Am J Cardiol.2007,Jun 15; 99(12):1656-61.Epub 2007 May 2.
  • 4Raff G L,Gallagher M J,O′Neill W W,et al.Diagnostic accuracy of noninvasive coronary angiography using 64-slice spiral computed tomography[J].J Am Coll Cardiol.2005,Aug 2; 46(3):552.
  • 5Mollet N R,Cademartiri F,van Mieghem C A,et al.High-resolution spiral computed tomography coronary angiographyin patients referred for diagnostic conventional coronary angiography[J].Circulation 2005 Oct 11; 112(15):2318.
  • 6Morgan-Hughes G J,Roobottom C A,Owens P E,et al.Highly accurate coronary angiography with submillimetre,16 slice computed tomography.Heart 2005 Mar; 91(3):308.
  • 7Martuscelli E,Romagnoli A,D′Eliseo A,et al.Accuracy of thin-slice computed tomography in the detection of coronary stenoses[J].Eur Heart J 2004 Jun; 25(12):1043.
  • 8Ropers D,Baum U,Pohle K,et al.Detection of coronary artery stenoses with thin-slice multi-detector row spiral computed tomography and multiplanar reconstruction[J].Circulation 2003 Feb 11; 107(5):664.
  • 9Detre K M,Wright E,Murphy M L,et al.Observer agreement in evaluating coronary angiograms Circulation,1975,52(6):979.
  • 10Sirol M,Sanz J,Henry P,et al.Evaluat 64-slice MDCT in the real world of cardiology:A comparison with conventional coronary angiography[J].Arch Cardiovasc Dis.2009 May; 102(5):433.

同被引文献57

  • 1姚伟,李慧芳.16层螺旋CT在检测老年原发性高血压患者冠状动脉病变中的临床应用[J].医学影像学杂志,2012,22(2):272-274. 被引量:4
  • 2黄斌,唐震.螺旋CT在冠心病诊断中的应用价值及心率对其的影响[J].海南医学,2006,17(5):5-8. 被引量:3
  • 3宋玮,金叔宣,杜勇平,刘建平,何奔,王彬尧.CT血管造影在评价冠状动脉支架术后支架内再狭窄中的价值[J].上海交通大学学报(医学版),2006,26(10):1172-1175. 被引量:5
  • 4陈在熹,高润霖冠心病[M]北京:人民卫生出版社,2002:745-146.
  • 5Wolf F, Cademartiri F, Loewe C, et al. Evaluation of coronary stents with 64-MDCT: in vitro comparison of scanners from four vendors[J]. AJR Am J Roentgenol, 2009,193 (3) : 787-794.
  • 6Chabbert V, Carrie D, Bennaceur M, et al. Evaluation of in-stent restenosis in proximal coronary arteries with multidetector computed tomography (MDCT) [J]. Eur Radiol, 2009,17 (6) : 1452-1463.
  • 7Oncel D, Oncel G, Karaca M. Coronary stent patency and in-stent restenosis: determination with 64-section multidctector CT coronary angiography-initial experience[J]. Radiology, 2008,242: 403-409.
  • 8Rixe J,Achenbach S, Ropers U, et al. Assessment of coronary artery stent restenosis by 64-slice multi-detector computed tomography[J] , Eur Heart J, 2008, 21: 2567-2572.
  • 9Ehara M, Kawai M, Surmely JF, et al. Diagnostic Accuracy of Coronary In-Stent Restenosis Using 64-Slice Computed Tomography[J]. J Am Coll Cardiol, 2009. 49: 951-959.
  • 10Sheth T, Dodd JD, HoHmann U, et al. Coronary stent asseseahility by 64 slice multi-detector computed tomography[J]. Catheter Cardiovasc Interv, 2007, 69 (7) : 933-938.

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