摘要
NCCN结肠癌临床实践指南是基于丰富循证医学证据建立的高水平、规范化治疗指南。近年来,随着临床证据的不断丰富和积累,指南对一些临床问题的处理进行了调整,有的原则发生了变化。本文通过对历年不同版本指南的比较,对手术方式及病理评估、术后辅助化疗、晚期治疗方案和分子靶向治疗等几方面指导意见的变化进行了初步探讨分析。
NCCN Clinical Practice Guidelines in Oncology, which based on abundant evidence of EBM, provide a concise script to help us understand colon cancer. With the clinical evidence accumulated, management of some problem has been adjusted and some principles have been changed. Through comparing of the guidelines in different version, we analyze the change on principle of surgery and pathologic evaluation, adjuvant chemotherapy, management of disseminated metastatic colon cancer and molecular targeted therapy to direct our clinical work.
出处
《医学与哲学（B）》
2010年第3期11-13,47,共4页
Medicine & Philosophy(B)
关键词
结肠癌NCCN临床实践指南
变化
探讨
NCCN Clinical Practice Guidelines in Oncology, change, analysis
