摘要
目的:观察类人胶原蛋白原液对人眼周皮肤皱纹的疗效及安全性。方法:招募29名健康受试者,左右侧眼周皮肤随机给予类人胶原蛋白原液导入治疗(治疗侧)及蒸馏水导入治疗(对照侧),每日1次,共2周。于治疗前后,医生进行主观评价、仪器检测皮肤红斑指数(erythemaindex,EI)及角质层含水量,于治疗后由受试者进行满意度评价。结果:治疗侧导入治疗2周后,医生评价明显改善者0例,中度改善者6例(20.69%),轻度改善者18例(62.07%);受试者满意率为89.66%。治疗侧与对照侧EI差值及角质层含水量差值无显著差异。仅17.2%受试者治疗侧有暂时性轻微刺痛感,无其他不良反应发生。结论:类人胶原蛋白原液可一定程度地改善眼周皮肤皱纹,且不良反应轻微。
Objective To observe the efficay and safety of Human-like collagen on removing wrinkles around the eye. Methods Twenty-nine healthy volunteers were recruited. One side of face was treated with the Human-like collagen by the way of iontophoresis once a day for a consecutive 2 weeks, according to a randomisation table. The other side was treated with water and observed as the self control. Before and after each procedure, skin color and water content were measured with Mexameter （EI：erythema index） and corneometer, individually. The global assessment were performed both by dermatologist and by all the volunteers. Results After 2 weeks＇ treatment, Dermatologist assessed that none of patient has obvious improve, 6 （20.69% ） and 18 （62.07% ） patients have mild and moderate improve, respectively. and patients self-evaluation was 89.66% . The mean EI value and water content did not change differently between the two sides. Conclusion Human-like collagen could effectively and safely remove wrinkles. The side-effects were transient and limited.
出处
《中国美容医学》
CAS
2010年第3期361-363,共3页
Chinese Journal of Aesthetic Medicine
基金
2007年教育部创新团队基金(IRT0760)
关键词
类人胶原蛋白
皱纹
离子导入
Human-like collagen
removing wrinkles
iontophoresis
