摘要
为探讨肺容积减少术治疗晚期慢性阻塞性肺病的疗效。１９９６年７月至１９９７年１０月期间为７例慢性阻塞性肺病病人施行肺容积减少术，其中同期双侧３例，单侧４例。为控制肺切面漏气，采用钳闭器并衬以牛心包片。切除一侧肺容积约２０％～３０％。结果：无手术死亡。２例术后并发急性呼吸衰竭，治愈。随访４～１６个月，平均９．９个月。ＦＥＶ１和ＭＶＶ分别增加了７６．４％和２５．４％，ＲＶ和ＴＬＣ明显下降（２．７％和１７．１％），ＰａＯ２增加了１．４４ｋＰａ，病人气急好转，活动能力及生活质量提高。本组随访期较短。
Aim:To evaluate the clinical results of lung volume reduction surgery(LVRS)for severe chronic obstructive pulmonary disease(COPD).Clinical material and method:From July 1996 to October 1997,7 patients with severe COPD underwent lung volume reduction surgery.The LVRS was performed unilaterally in 4 via posterolateral thoracotomy and bilaterally in 3 through median sternotomy.20%～30% of total volume of each lung were resected.Linear stapling device and bovine pericardium were used for elimination the airleak of resected margin.Result:There was no operative death.Postoperative complications included acute respiratory failure in 2 and persistent airleak in 3.All patients were followed up for 4 to 16 months(mean 9.9 months).After surgery,the mean forced expiratory volume in 1 second(FEV 1)and MVV were significantly increased by 76.4% and 25.4%,respectively.Total lung capacity(TLC)and residual volume(RV)were markedly decreased by 2.7% and 17.1%,respectively.PaO 2 was increased by 8.55mmHg.Six minute walk test was significantly improved.Conclusion:The preliminary results of this study suggest that LVRS,as a palliative therapy,is an effective and safe method for selective patients with severe COPD.It can provide significant functional benefits and symptomatic relief.
出处
《中华胸心血管外科杂志》
CSCD
北大核心
1998年第6期353-355,共3页
Chinese Journal of Thoracic and Cardiovascular Surgery
关键词
肺容积减少术
慢性阻塞性肺病
Lung volume reduction surgery Chronic obstructive pulmonary disease
