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食管癌化疗敏感性预测及预后分子靶点研究进展 被引量:4

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摘要 随着食管癌发生、发展过程中分子生物学机制研究不断深入,与食管癌化疗敏感性及预后相关的分子靶点正在逐步为临床的诊疗提供参考依据。研究主要集中在突变型p53基因、表皮生长因子受体(epidermal growth factor receptor,EGFR)、血管内皮生长因子(vascular endothelial growth factor,VEGF)、COX-2等靶点,
出处 《癌症进展》 2010年第2期143-147,共5页 Oncology Progress
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参考文献29

  • 1Liu YS, Yu CH, Li L, et al. Expression of p53, p16 and cyclooxygenase-2 in esophageal cancer with tissue mieroarray [J].J Digest Diseases, 2007, 8 : 133.
  • 2Weston AP, Banerjee SK, Sharma P, et al. p53 protein overexpression in low grade dysplasia (LGD) in Barrett's esophagus : Immunohistochemical marker predictive of progression [J]. Am J Gastroenterol, 2001, 96 : 1355.
  • 3Shimada H, Shiratori T, Takeda A, et al. Perioperative changes of serum p53 antibody titer is a predictor for survival in patients with esophageal squamous cell carcinoma [J]. World Surgery, 2009, 33 (2):272.
  • 4Miyawaki M, Hijiya N, Tsukamoto Y, et al. Enhanced phosphorylation of the epidermal growth factor receptor at the site of tyrosine 992 in esophageal carcinomas [ J ]. APMIS,2008, 116 (12):1097.
  • 5Gibauh L, Metges J P, Conan-Charlet V, et al. Diffuse EGFR staining is associated with reduced overall survival in locally advanced oesophageal squamous cell cancer [ J ]. Br J Cancer, 2005, 93 : 107.
  • 6Hoshino M, Fukui H, Ono Y, et al. Nuclear expression of phosphorylated EGFR is associated with poor prognosis of patients with esophageal squamous cell carcinoma [ J ]. Pathobiology, 2007, 74 : 15.
  • 7Gotoh M, Takiuchi H, Ichiro S, et al. Epidermal growth factor receptor is a possible predictor of sensitivity to chemoradiotherapy in the primary lesion of esophageal squamous cell carcinoma [J]. Jpn J Clin Oncol, 2007, 37 (9):652.
  • 8Takayuki Kii, Hiroya Takiuchi, Shinichiro Kawabe, et al. Evaluation of prognostic factors of esophageal squamous cell carcinoma ( stage Ⅱ-Ⅲ) after concurrent chemoradiotherapy using biopsy specimens [ J ]. Jpn J Clin Oncol, 2007, 37 (8):583.
  • 9Yukie Sato-Kuwabara, Jose I Neves, Jose HTG Fregnani, et al. Evaluation of gene amplification and protein expression of HER-2/neu in esophageal squamous cell carcinoma using fluorescence in situ hybridization (FISH) and immunohistochemistry [J]. BMC Cancer, 2009, 1 (9):6.
  • 10Lagarde SM, Kate FJW, Richel D J, et al. Molecular prognostic factors in adenocarcinoma of the esophagus and gastroesophageal junction [ J ]. Ann Surg Oncol, 2007, 14 (2):977.

二级参考文献37

共引文献43

同被引文献49

  • 1陆楷,王文敬,.p53蛋白在食管癌诊断中的应用[J].现代医学仪器与应用,2008,0(1):18-20. 被引量:2
  • 2黄诗良,孟祥中.早期食管癌的诊断[J].现代实用医学,2005,17(9):528-529. 被引量:9
  • 3李辉,阎天生,张晓娜.食管癌早期诊断的研究进展[J].河北医药,2006,28(8):755-757. 被引量:7
  • 4杨军,高荣,乔鹏飞,张建国,陈书山,高旭东.食管癌影像学分期及手术后病理分期对比研究[J].内蒙古医学院学报,2006,28(5):449-453. 被引量:3
  • 5贺小停,曹秀峰.miRNA与食管癌[J].世界华人消化杂志,2007,15(19):2133-2137. 被引量:7
  • 6Lee MH, Lozano G. Regulation of the p53 MDM2 pathway by 14-3-3 sigma and other proteins. Semin Cancer Biol, 2006, 16: 225- 234.
  • 7He L, He X, Lim LP, et al. A microRNA component of the p53 tumour suppressor network. Nature, 2007, 447:1130- 1134.
  • 8Liu YS, Yu CH, Li L, et al. Expression of p53, p16 and cyclooxygenase-2 in esophageal cancer with tissue microarray. J Dig Dis, 2007, 8:133- 138.
  • 9Chava S, Mohan V, Shetty PJ, et al. Immunohistochemical evaluation of p53, FHIT and IGF2 gene expression in esophageal cancer. Dis Esophagus, 2012, 25: 81- 87.
  • 10Fagundes RB, Mello CR, Tollens P, et al. p53 protein in esophageal mucosa of individuals at high risk of squamous cell carcinoma of the esophagus. Dis Esophagus, 2001, 14: 185- 190.

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