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血管性认知障碍非痴呆患者血浆Lp-PLA2活性变化的初步探讨 被引量：6

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摘要 目的探讨血管性认知障碍非痴呆患者(VCIND)血浆脂蛋白相关磷脂酶A2(Lp-PLA2)的变化特征。方法采用病例—对照研究方法,病例组为VCIND患者60例,对照组为健康体检者60例。记录两组认知障碍相关临床危险因素,并进行MoCA量表评分和Lp-PLA2活性检测。结果与对照组比较,病例组血浆Lp-PLA2活性较高(P<0.05)。Lp-PLA2活性与VCIND危险因素中的TC、LDL-C、HDL-C的相关性最强。结论VCIND患者血浆Lp-PLA2活性升高,后者与VCIND危险因素有相关性。
作者 张洪涛 张道培 张淑玲 付胜奇
机构地区 郑州人民医院
出处 《山东医药》 CAS 北大核心 2010年第12期86-87,共2页 Shandong Medical Journal
关键词 痴呆 血管性 认知障碍 脂蛋白相关磷脂酶A2
分类号 R749.1 [医药卫生—神经病学与精神病学]
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参考文献7

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共引文献46

同被引文献54

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引证文献6

二级引证文献22

山东医药
2010年 第12期

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