摘要
目的研究组织型纤维蛋白溶酶原激活剂（t—PA）和六氟化硫（SF6）玻璃体腔内注射治疗外伤性黄斑部视网膜下出血的临床效果。方法外伤性黄斑部视网膜下出血50例（50眼）。随机分为2组，A组：t—PA和SF6治疗组；B组：空白对照组。t—PA和SF6注射量分别为25～50μg（0．1mL）和SF6 0．5mL。结果治疗后10d：治疗组和对照组出血吸收情况差异有统计学意义（P〈0．05）；治疗后1、3个月：两组出血吸收情况差异有统计学意义（P〈0．01）。治疗前、后两组裸眼视力差异有统计学意义（P〈0．01）。未见并发症。结论t—PA联合SF6玻璃体内注射治疗黄斑部视网膜下出血是一种简便、安全、有效的方法。
Objective To explore the clinical effects of injection of t - PA and gas of SF6 to treat retinal submacular hemorrhage of trauma. Methods 50 eyes with retinal sub - Group - A treated with t - PA and SF6 ; Group B （ the contrast group）. The injection doses oft -PA and SF6 were 25 -50ug （0. lml） and 0. 5ml respectively. Results 10 days of treatments showed sta-tistical significance in terms of the absorption of hemmorhage. （ P 〈 0.05 ）. The two groups showed significant differences one and three monthers later（ P 〈0. 01 ）. Group B gotobvious improvement in visal acuity after treatment （P 〈 0. 01 ） and no complications occurred. Conclusion Intravitreous injection of t - PA and SF6 can be used effectively to treat retinal submacular hemorrhage of trauma.
出处
《眼外伤职业眼病杂志》
2010年第3期174-177,共4页
Journal of Injuries and Occupational Diseases of the Eye with Ophthalmic Surgeries
