摘要
目的：探讨急性髂股静脉血栓形成患者血清β２微球蛋白（β２ＭＧ）和乳酸脱氢酶（ＬＤＨ）水平的变化及临床意义。方法：用放射免疫方法测定６０例急性髂股静脉血栓形成患者急性期、好转期、临床治愈期和治愈后１个月的血清β２ＭＧ和ＬＤＨ含量，并与３０例健康人作对照。结果：６０例患者血清β２ＭＧ为（５．９６±０．５６）ｍｇ／Ｌ，ＬＤＨ为（７９８．２２±６５．３２）Ｕ／Ｌ，均明显高于健康对照组〔（２．３１±０．６７）ｍｇ／Ｌ和（１９０．５９±８８．１３）Ｕ／Ｌ〕。结论：急性髂股静脉血栓形成患者存在高β２ＭＧ血症和高ＬＤＨ血症，且β２ＭＧ及ＬＤＨ与病情轻重和疾病转归密切相关。测定β２ＭＧ和ＬＤＨ可作为判断病情严重程度。
Objective:To investigate the changes and clinical significance in serum β 2microglobulin (β 2MG) and lactate dehydrogenase(LDH) levels in patients with acute iliofemoral thrombosis.Methods:During acute,recovery,cure stages and 1 month after cure in patients with acute iliofemoral thrombosis,serum β 2MG and LDH levels were determined in 60 cases by redioimmunoassay,and 30 healthy served as controls.Results:Serum β 2MG and LDH levels were (5 96±0 56)mg/L and (798 22±65 32)U/L respectively in patients with acute iliofemoral thrombosis,which were markedly higher than those in normal controls (2 31±0 67)mg/L and (190 59±88 13)U/L respectively .Conclusions:High levels of β 2MG and LDH might be related to the severity of disease in patients with acute iliofemoral thrombosis.Contents of serum β 2MG and LDH can serve as useful parameters to reflect the severity of disease and predict the prognosis.
出处
《中国危重病急救医学》
CSCD
1998年第8期490-492,共3页
Chinese Critical Care Medicine
关键词
乳酸脱氢酶
血栓形成
髂股静脉
Β2-MG
β 2microglobulin\ \ lactate dehydrogenase \ acute iliofemoral thrombosis
