摘要
目的:了解儿童呼吸道感染的病原体分布情况及感染率,为临床诊治提供依据。方法:利用生物芯片技术对513例呼吸道感染儿童进行血清6种病原体抗体检测。结果:抗体阳性患者达164例(占32.0%),其中有45例患者检出二种以上抗体(占8.8%),感染阳性率依次为副流感病毒11.3%、腺病毒8.8%、流感病毒8.0%、呼吸道合胞病毒7.0%、肺炎支原体6.0%和肺炎衣原体2.5%。结论:6种病原体的感染率大体一致,检测血清中IgM抗体的方法其阳性率较其它直接检测病原体的方法低,生物芯片技术在病原学快速诊断方面有较好的应用前景。
Objective：To understand the distribution of the respiratory tract infection pathogens in children and infection rates,furthermore to provide proof for clinical diagnosis and treatment.Methods：To detect six kinds of serum antibodies in 513 cases of children with respiratory tract infection pathogens using biochip technology.Results：Antibody-positive patients amount to 164 cases（32.0%）,which 45 cases were detected more than two kinds of antibodies（8.8%）,positive rate of infection was followed by Parainflu enza virus 11.3%,Adenovirus 8.8%,Influenza virus 8.0%,Respiratory syncytial virus 7.0%,6.0% Mycoplasma pneumoniae and Chlamydia pneumoniae 2.5%.Conclusion：The infection rate in the six pathogens were broadly consistented,positive rate of detected serum IgM antibody is low than other methods which directly detect pathogens,and biochip technology seemly have good application prospects in the rapid diagnosis of pathogens.
出处
《中国卫生检验杂志》
CAS
2010年第2期327-328,共2页
Chinese Journal of Health Laboratory Technology
关键词
呼吸道感染
生物芯片
病原体检测
儿童
Respiratory tract infections
Biochip
Pathogen detection
Children
