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两种胰岛素强化治疗对初诊2型糖尿病患者胰岛β细胞功能的影响 被引量:12

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摘要 目的探讨短期持续胰岛素输注(CSⅡ)及多次胰岛素皮下注射(MSll)对初诊2型糖尿病(T2DM)患者胰岛β细胞功能的影响。方法选取2007年1~12月在本院就诊的初诊2型糖尿病患者80例随机分为CSⅡ组及MSⅡ组治疗14天,比较两组治疗前后各项指标、稳态模型评估胰岛素抵抗指数(HOMA-IR),β细胞功能指数(HOMA-β);及两组达标时间,胰岛素用量,低血糖发生率,治疗费用。结果两组治疗前后HOMA-IR降低,HOMA—β增加,差异有统计学意义(P〈0.01);两组间治疗前后无差异(P〉0.05);两组达标时间,胰岛素用量,低血糖发生率,治疗费用差异有统计学意义(P〈0.01)。结论短期CSⅡ及MSⅡ强化治疗均可改善初诊断T2DM患者胰岛β细胞功能,减轻胰岛素抵抗,CSⅡ较MSⅡ疗效好。
机构地区 龙泉市人民医院
出处 《浙江实用医学》 2010年第1期29-30,共2页 Zhejiang Practical Medicine
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