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肥胖患者隐性高血压与胰岛素抵抗关系的初步探讨 被引量:5

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摘要 目的:探讨肥胖患者隐性高血压(masked hypertension,MH)与胰岛素抵抗的关系。方法:选取诊所血压(CBP)正常的肥胖患者67例(肥胖组)和体重正常的健康体检者29例(对照组),均行24h动态血压监测,按日间血压检测结果,将肥胖患者分为肥胖伴MH组(28例)和单纯肥胖组(39例);测定空腹血糖、血浆胰岛素(FINS)水平,采用稳态模式评估法(homeostasis model assessment)计算胰岛素抵抗指数(HOMA-IR),评价胰岛素抵抗。结果:肥胖伴MH组的24h平均收缩压、24h平均舒张压、日平均收缩压、日平均舒张压均明显高于对照组和单纯肥胖组(P<0.01);肥胖组的FINS、HOMA-IR均高于对照组,肥胖伴MH组升高更明显,与对照组与单纯肥胖组比较,差异均有显著性(均P<0.01)。结论:胰岛素抵抗可能是肥胖患者合并MH的危险因素之一。
出处 《实用医学杂志》 CAS 北大核心 2010年第4期604-605,共2页 The Journal of Practical Medicine
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