摘要
目的探讨胚胎解冻移植周期血E2、P及其比值与自然周期解冻移植结局的关系。方法对北京大学第三医院自2008年1月至2008年10月自然周期方案行胚胎解冻移植的742个周期进行总结分析。根据移植后的临床结局分为妊娠组(331例,又分宫内活胎组及妊娠结局不良组)及未妊娠组(411例),分别于移植当日及移植后3天取血查血清雌二醇(E2)和孕激素(P)。结果本组解冻移植后临床妊娠率为33.42%;移植后妊娠与否与是否发生卵泡黄素化无关,P>0.05;宫内活胎组移植日P/E2值为117.6±71.5,移植后3天的E2、P、P/E2分别为628.2±329.4,90.6±61.8,及161.2±104.9,明显低于未妊娠组,P<0.05。结论自然周期胚胎解冻移植当日及移植后3天周期恰当的雌孕激素比例与胚胎解冻移植临床结局有关。
Objective： To investigate the relationship of serum progesterone and estradiol level on the clinical outcomes of frozen thawed embryo transfer in nature cycles. Methods： 742 FET cycles were analyzed, 331 of them were pregnant, and 411 non pregnant. Serum progesterone and estradiol level were measured on the day of embryo transfer and 3 days after embryo transfer. Results： Total clinical pregnancy rate was 33.42% in our study. P/E2 ratio was 117. 6 ±71.5 on the day of embryo transfer in the group of intrauterine pregnancy with live fetus, and the E2, P, P/E2 were 628. 2 ±329.4, 90. 6 ±61.8 and 161.2 ± 104. 9 respectively 3 days after embryo transfer, both have significant difference compared with non pregnant group. Conclusion： The appropriate progesterone and estradiol level was correlated with FET outcomes in nature cycle.
出处
《中国优生与遗传杂志》
2010年第3期127-128,151,共3页
Chinese Journal of Birth Health & Heredity
关键词
胚胎解冻移植
血清E2
血清P
妊娠结局
Frozen thawed embryos transfer （FET）
Serum estradiol level
Serum progesterone level
Clinical outcomes
