摘要
虽然近十年来心力衰竭药物治疗取得了重大进展,但心力衰竭仍然是危害公众健康、临床预后极差的综合病症。阻断肾素-血管紧张素-醛固酮以及交感神经的药物可以抑制心室重构、改善心功能、减轻症状并能延长存活率。利尿剂、血管扩张剂和强心类药物仅能改善临床症状而不影响预后。新的药物对于终点事件的影响仍在研究探索中。
Despite of great advances in drug management of heart failure in the past ten years, the condition remains a major public health issue, with high prevalence, poor clinical outcomes. Treatment of established systolic chronic heart failure includes agents that block the renin-ngiotensin-aldosterone and sympathetic nervous systems to prevent adverse remodelling, to reduce symptoms and prolong survival. Diuretics, Vasodilator and Digoxin are often used to improve sign,with no influence on prognosis. Pharmacological agents aimed at new targets on clinically relevant endpoints are going under investigating.
出处
《中国实用内科杂志》
CAS
CSCD
北大核心
2010年第3期206-209,共4页
Chinese Journal of Practical Internal Medicine
关键词
心力衰竭
药物治疗
heart failure
drug therapy
