摘要
目的检测子宫颈癌患者放疗前后血清铜、锌的变化，检测子宫颈癌患者与正常人血清铜、锌水平的比较。材料与方法采用三电极直流等离子原子发射光电直读光谱仪法检测。结果子宫颈鳞癌患者血清铜（ＳＣｕ）、铜锌比值（Ｃｕ／Ｚｎ）显著高于正常对照组（Ｐ＜０．００１），Ⅲ期患者又显著高于Ⅱ期患者（Ｐ＜０．００１）；放疗后癌灶完全消退者（ＣＤ）ＳＣｕ、Ｃｕ／Ｚｎ明显下降（Ｐ＜０．０１）；部分消退者（ＰＤ）二值仍处于高水平。结论：ＳＣｕ和Ｃｕ／Ｚｎ可以检测放疗疗效，估计预后，有一定临床意义。
s Three electrodes-direct current-plasma-atom launching-photoelectricity spectrograph was readed directly to determine the trace elements for twenty-eight patients with squamous cell carcinoma of cervix uteri before and after radiotherapy. The results showed that the serum copper level (SCL) and copper/zinc (Cu/Zn ) ratio of cervical cancer were all higher than those of normal ranges, and those of Ⅲwere also higher than those of Ⅱ; After radiotherapy both in complete diasppearance(CD) were all obviously dropped while they were still high in partial disappearance (PD). So SCL and Cu/Zn ratio may be used to monitor the radiotherapeutic effects.
关键词
鳞癌
放射疗法
铜
锌
子宫颈肿瘤
Squamous cell carcinoma of cervix uteri Radiotherapy Copper Zinc
