摘要
[目的]了解接种乙肝疫苗后儿童乙肝发病特征及其发生的变化，为今后的乙肝防治提供科学依据。[方法]对1982-2008年普兰店市15岁以下儿童乙肝疫情资料进行分析。[结果]1982～2008年合计报告15岁以下儿童乙肝病人546例，年均发病率为14．40／10万。其中，1993年最高（30．56／10万），2007年最低（0．00／10万）；男性为3．24／10万．女性为1．72／10万（P〈0．01）；0～4岁为8．15／i0万，5～9岁为18．16／i0万，10～14岁为16．GS／10万（P〈0．01）。15岁以下儿童乙肝年发病率与该人群乙肝疫苗年接种率呈高度负相关（P〈0．01）。[结论]15岁以下儿童乙肝发病率有明显下降趋势，乙肝发病率与乙肝疫苗接种率呈高度负相关。
[Objective]To understand the epidemiological characteristic of hepatitis B （HBV）in children after hepatitis B vaccination, to provide scientific basis for hepatitis B control and prevention. [Methods] Hepatitis B epidenfic data in children aged under 15 from 1982 to 2008 were analyzed. [Results]A total of 546 hepatitis B cases in children aged under 15 were reported from 1982 to 2008, the average annual incidence rate was 14.40/100 000, of them, the highest incidence was in 1993 （30.56/100 000）,while the lowest incidence was in 2007 （0.00/100 000）.The incidence was 3.24/100 000 and 1.72/100 000 in male and female （ P 〈0.01）. It was 8.15/100 0000,18. 16/ 100 000 and 16.68/100 000 in the children aged 0-4,5-9 and 10-14 years old （ P 〈0.01）. There were significantly negative correlation between the prevalence of hepatitis B and hepatitis B vaccine coverage in children under 15 （ P 〈0.01）. [Conclusion]The prevalence of hepatitis B was going down in children aged under 15. There were significantly negative correlation between the prevalence of hepatitis B and hepatitis B vaccine coverage.
出处
《预防医学论坛》
2010年第3期279-280,282,共3页
Preventive Medicine Tribune
关键词
儿童
乙型肝炎
乙肝疫苗
流行特征
Children
Hepatitis B
HB vaccine
Epidemiological characteristic
