摘要
目的 回顾研究已绝经与未绝经子宫内膜癌的病理分型,组织分级和手术病理分期等.方法 分析1987年1月～1996年12月上海第一妇婴保健院收治的138例子宫内膜癌患者,其中已绝经者93例,未绝经者45例.所有的病人都进行了分段诊刮,134例经过手术治疗.标本均进行了病理诊断,并根据1988年FIGO标准进行分期,所得资料用X^2Fisher’s exact test分析.结果 已绝经组与未绝经组比较,早期患者(IaG_1)比例明显偏低,分别占6%与32%.(P<0.001).G_2、G_3和非内胰腺癌的发生率是高的,分别是71%和51%(P<0.05).Ⅰc、Ⅱ、Ⅲ、Ⅳ期所占的比例较大,分别是40%和30%(P<0.001).五年生存率:已绝经组为74.2%,未绝经组91.4%,两者比较有明显意义(P<0.05).结论 已绝经子宫内膜癌患者预后较未绝经者差与临床和病理特点有关.
PURPOSE To review the pathology type, histology grade and operative pathology stage, etc. of endometrial carcinoma (EC) of nonmenopause and menopause patients. METHODS A total of 138 patients with EC treated in First Maternity and Infant Health Hospital of Shanghai from January 1987 to December 1996 were analyzed. Of them. 93 were in menopausal group and 45 in non menopausal group. Fractional curettage of the uterus was performed in all patients, and surgical treatment was performed in 134 cases. The specimens were pathologically diagnosed and staged according to FIGO (1998). The data were analyzed for statistical significance using X2 Fisher's test. RESULTS When the menopausal group was compared with the nonmenopausal group, the rate of stage la. G1 was lower. being 6% versus 32% (P<0. 001). The incidence of G2. G3 non-endometrioid EC was higher, being 71% versus 51% (P<0. 05). The rate of patients with stage Ⅰc. Ⅱ . Ⅲ , Ⅳ was higher, being 40% and 30%, respectively (P<0. OOP. The five years survival rate was lower, being 74.2% versus 91.4% (P<0. 05), CONCLUSION The clinical and pathological characteristics of endometrial carcinoma might be responsible for the poorer prognosis of menopausal patients compared with nonmenopausal.
出处
《中国癌症杂志》
CAS
CSCD
1998年第4期274-276,共3页
China Oncology
关键词
子宫内膜癌
绝经
临床
病理
Endometrial carcinoma (EC) Nonmenopause Menopause Clinic Pathology
