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轻度认知损害的诊断与评估 被引量：37

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摘要 轻度认知损害（mild cognitive impairment, MCI）是介于正常老化与痴呆之间的过渡阶段。关于MCI的诊断从狭义的角度，MCI迟早演变为痴呆；而从广义的角度，MCI是一个认知功能损害程度轻重不等、损害领域各异的内涵广泛的群体，是一种综合征。其既可以快速进展至痴呆（痴呆前驱期），也可以长期保持不变（稳定型MCI），甚至部分可逆转为正常。
作者 郭起浩 洪震
机构地区 复旦大学附属华山医院神经内科
出处 《中华神经科杂志》 CAS CSCD 北大核心 2010年第3期169-170,共2页 Chinese Journal of Neurology
关键词 轻度认知损害 诊断 认知功能损害程度 评估 MCI 正常老化 痴呆 综合征
分类号 R749.1 [医药卫生—神经病学与精神病学]
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参考文献12

  • 1Petersen RC.Mild cognitive impairment as a diagnostic entity.J Intern Med,2004,256:183-194.
  • 2Petersen RC,Smith GE,Waring SC,et al.Mild cognitive impairment:clinical characterization and outcome.Arch Neural,1999,56:303-308.
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  • 7袁晶,付建辉,郭起浩,洪震.遗忘型轻度认知损害和非痴呆血管性认知损害的局部脑血流量[J].中华神经科杂志,2008,41(10):678-682. 被引量：8
  • 8吴小三,程怀东,汪凯.轻度认知功能障碍的记忆监测[J].中华医学杂志,2009,89(15):1037-1040. 被引量：9
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二级参考文献62

  • 1Winblad B, Palmer K, Kivipelto M, et al. Mild cognitive impairment-beyond controversies, towards a consensus: report of the International Working Group on Mild Cognitive Impairment. J Intern Med, 2004, 256: 240-246.
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  • 6Petersen RC. Mild cognitive impairment as a diagnostic entity. J Intern Med, 2004, 256: 183-194.
  • 7Reiman EM, Caselli R J, Yun LS, et al. Preclinical evidence of Alzheimer' s disease in persons homozygous for the epsilon 4 allele for apolipoprotein E. N Engl J Med, 1996, 334: 752-758.
  • 8Amaiz E, Jelic V, Almkvist O, et al. Impaired cerebral glucose metabolism and cognitive functioning predict deterioration in mild cognitive impairment. Neuroreport, 2001, 12: 851-855.
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共引文献40

同被引文献376

引证文献37

二级引证文献296

中华神经科杂志
2010年 第3期

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