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原发性高血压患者血清8-异构前列腺素F2α测定的临床意义

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摘要 目的探讨原发性高血压患者血清中8-异构前列腺素F2α（8-iso—PGF2α）改变的临床意义。方法选取124例原发性高血压患者（分为1，2，3级）和50例正常健康者，应用双抗体夹心酶联免疫吸附法（ELISA）检测患者血清8-iso—PGF2α的水平。结果原发性高血压1级、2级和3级患者的血清8-iso—PGF2α水平分别为（18．5±4．7）ng／L、（29．3±7．7）ng／L和（40．8±10．6）ng／L，其差异均具有统计学意义（P〈0．05）；原发性高血压患者的血清8-iso—PGF2α水平高于正常对照组（P〈0．05），且与血压水平呈正相关（r=0．385，P〈0．05）。结论血清8-iso—PGF2α水平增高与原发性高血压病程呈正相关，有利于高血压病情的评估。
作者 刘建武
机构地区 湖南省绥宁县人民医院
出处 《中国医学创新》 CAS 2010年第8期118-119,共2页 Medical Innovation of China
关键词 原发性高血压 8-异构前列腺素F2α 病情评估
分类号 R544.1 [医药卫生—心血管疾病]
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参考文献6

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中国医学创新
2010年 第8期

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