摘要
目的探讨2型糖尿病（T2DM）患者体脂肪量、分布与其胰岛B细胞功能相关性。方法用体重脂肪测定仪测量67例T2DM患者的体脂肪牢、体脂肪含量，测身高、体重、腰出、臀围，计算体重指数、腰臀比。作标准馒头试验和精氨酸刺激试验，分别检测各时断分泌的C肽，计算C肽曲线下的面积。结果WHR、WC、BMI、FAT、FATMASS与0hC肽、2hC肽、标准馒头试验和精氨酸刺激试验洲得的C肽曲线下的面积呈正相关（P〈0．05）。结论体脂增多，尤其是腹部脂肪增多，加重T2DM患者胰岛B细胞的负担，是T2DM患者胰岛素抵抗的重要危险因素。
Objective To investigate the relation of body fat content and distribution with pancreatic β -cell function of type 2 diabetics.Methods FAT, FATMASS were measured with TBF-3OOGS in 67 type 2 diabetic cases Height , body weight and waist circumference were also measured to calculate BMI and WHR.Standard steamed bread Test and arginine stimulation test were done in the cases to measure plasma glucose and C-peptide of every time scale, then to calculate Area under a curve of C-peptide. Results WHR, WC, BMI, FAT, FATMASS were correlated positively withO hours C-tipetide, 2 hours C-peptide, Area under a curve of C-peptide which measured by Standard steamed bread Test and arginine stimulation test, （ P 〈 0.05 ）.Conclusions Increasing body fat, especial increasing area of abdominal fat, will increase the B cell of pancreas＇ s work, which is an important risk factor of insulin resistance tot type 2 diabetics.
出处
《国际医药卫生导报》
2010年第5期527-529,共3页
International Medicine and Health Guidance News
关键词
2型糖尿病
体脂
胰岛B细胞
Diabetes mellitus of Type 2
Body fat
Pancreatic β-cell function
