摘要
采用8种合成方法,合成了38种α-氨基膦(次膦)酸类衍生物。发现部分α-氨基膦酸化合物中含有1个结晶水。测定了化合物的pK_α值。所有化合物都具有一定除草和杀菌活性。
38 Derivatives of a-amino phospho(i)nic acids(RCH(NH2)-P(O) -(OH)R' ,R,R' =alkyl or aryl) have been synthesized by the addition reaction of the phosphorous compounds containing P-H bond to imine compounds in which the imino group was protected with actyl or carbobenzyloxy group. The products could be purified by recrystallization, ion exchange technique or repeated acid-base neutralization. Some of the a-amino phosphonic acids contain one moleculer of water when they were recrystallized from a mixture of alcohol and water. The pKa values of the title compounds have been measured. It has been found that all of these compounds have herbicidal and fungicidal activities.
出处
《高等学校化学学报》
SCIE
EI
CAS
CSCD
北大核心
1989年第3期254-259,共6页
Chemical Journal of Chinese Universities
基金
国家自然科学基金
关键词
氨基膦酸
合成
杀菌活性
除草活性
a-Amino phospho(i)nic acid, Synthesis, Crystal water, pKa, Herbicidal and fungicidal activities
