摘要
目的分析子宫颈癌术后放疗及各项因素与远期疗效的关系，并与单纯放疗、单纯手术及术前放疗的疗效作对比分析。材料与方法１９８５年至１９９３年对１２０例宫颈癌进行了术后放疗，其中Ⅰ期２３例，Ⅱ期９７例。鳞癌１１２例，腺癌８例，均为浸润深肌层。盆腔有淋巴转移３０例。放疗采用６０Ｃｏ全盆外照射，肿瘤量４１～５９Ｇｙ１０６例占８８．３％。结果生存５年以上者９９例，５年生存率为８２．５％。年龄、期别、肿瘤大小、病理类型、手术方式与远期疗效无明显相关。有、无淋巴转移的５年生存率分别为６３．３％和８８．９％（Ｐ＜０．０１）。放疗剂量为４１～５９Ｇｙ组的５年生存率明显高于大于或小于该剂量组，分别为９１．６％和５７．１％（Ｐ＜０．０５）。结论本组术后放疗与文献中单纯放疗、单纯手术的远期疗效进行比较显示：Ⅰ期、Ⅱａ期病例无差异，Ⅱｂ期单纯放疗为好。
Purpose To evaluate the effects of the postoperative radiotherapy in treatment of cervical carcinoma.Materials and Methods From 1985 through 1993,120 patients with cervical carcinoma were treated by postoperative radiotherapy. Among them ,23 cases were stage Ⅰ,97 cases stage Ⅱ. There were 112 cases with squamous cell carcinoma, 8 cases with adenocarcinoma. Pelvic lymph nodes were involved in 30 cases. The whole pelvis external irradiation was used. Radiotherapy dosage was 41 to 59 Gy in 106 cases .Results The 5 year survival rate was 82.5%(99/120). There was no evident relation between the long term survival and the size of tumor, pathological types and the surgical methods. The 5 year survival rates of the patients with or without lymph node involvement were 63.3% and 88.9% ,respectively(P< 0.01 ).Conclusion Comparing our results with those of radiation alone,surgery alone and preoperative radiation plus operation in literature we suggest that it is not necessary to use the postoperative radiation for patients with stage Ⅰ and stage Ⅱa cervical carcinoma and it is better to use radiation alone for stage Ⅱb patients.
出处
《中华放射肿瘤学杂志》
CSCD
北大核心
1998年第4期236-238,共3页
Chinese Journal of Radiation Oncology
关键词
宫颈肿瘤
放射疗法
术后
疗效
Cervix neoplasms/radiotherapy Cervix neoplasms/surgery
