摘要
目的：观察中西医结合治疗对急性心肌梗死（ＡＭＩ）患者心功能的影响。方法：ＡＭＩ患者５６例，在发病的前２周均按常规治疗，从第３周开始将患者随机分成中西医结合组２９例和西医组２７例，西医组治疗同前，中西医结合组每日加服中药１剂。采用二维超声心动图分别记录２组患者治疗前后心功能各项指标。结果：中西医结合组治疗后每搏输出量〔（７３．５±６．０）ｍｌ〕、每分输出量〔（５．４３±０．３４）Ｌ／ｍｉｎ〕、射血分数（０．５３±０．０９）均明显增高，舒张末期容积〔（７４．６±２３．８）ｍｌ〕和收缩末期容积〔ＥＳＶ，（３６．６±１６．８）ｍｌ〕均明显降低，与治疗前〔分别为（３９．９±５．８）ｍｌ，（３．２１±０．２８）Ｌ／ｍｉｎ，０．４６±０．０９，（８２．８±２８．２）ｍｌ和（４４．６±１８．９）ｍｌ〕比较，Ｐ均＜０．０１，与西医组治疗后〔分别为（６４．８±６．１）ｍｌ，（４．６３±０．４０）Ｌ／ｍｉｎ，０．４６±０．０９，（８８．３±２４．９）ｍｌ和（４９．６±１５．８）ｍｌ〕比较，Ｐ均＜０．０５。结论：益气活血中药在抑制左心室的进一步扩张，减少ＥＳＶ，减轻心脏变形，改善局部和整体室壁运动以及左心室收缩功能方面有明显疗效。
Objective:To observe the effect of TCM WM treatment on cardiac function in patients with acute myocardial infarction (AMI).Methods:Fiftysix cases of AMI were treated with conventional therapy for 2 weeks after onset,from third weeks patients were divided into TCM WM group ( 29 cases ) and WM group (27 cases).The TCM WM group was treated with TCM recipe daily on the basis of routine therapy,then to record cardiac function parameters using twodimentional ultrasonic echocardiography preand post therapy.Results:There were obvious raised of stroke volume ( 73 5±6 0)ml ,cardiac output (5 43±0 34)L/min ,ejection fraction (0 53±0 09)and marked decreased in enddiastolic volume (74 6±23 8)ml and endsystolic volume ESV,(36 6±16 8) ml after therapy in TCM WM group,they were all P <0 01 as compared to before treatment (39 9±5 8)ml,( 3 21±0 28 )L/min,0 46±0 09,(82 8±28 2)ml and (44 6±18 9)ml respectively and all P <0 05 as compared to WM group post therapy (64 8±6 1)ml,(4 63±0 40)L/min,0 46±0 09,(88 3± 24 9) ml and (49 6±15 8)ml respectively .Conclusions:There are obvious therapeutic efficacy of Yiqi Huoxue (益气活血) recipe in preventing left ventricular dilatation further,decreasing ESV,reducing cardiac deformation,improving local and entire ventricular wall motion and ameliorating left ventricular systolic function.
关键词
心肌梗死.急性
益气活血
心功能
中西医结合疗法
acute myocardial infarction\ \ Yiqi Huoxue\ \ cardiac function\ \ TCM WM therapy
