摘要
目的:观察泮托拉唑对十二指肠溃疡的疗效及作用机制。方法:收集200例十二指肠溃疡患者,随机分为观察组和对照组,观察组(100例)应用以泮托拉唑为主的综合治疗,对照组(100例)应用以奥美拉唑为主的综合治疗,观察2组的疗效、副作用及对黏膜炎症的作用。结果:观察组的总有效率(96.84%)明显优于对照组(85.26%),治疗后观察组的炎症反应(20.00%)明显低于对照组(45.98%),且副作用小。结论:泮托拉唑治疗十二指肠溃疡,疗效显著,副作用小,对黏膜的炎症有良好的控制作用。
OBJECTIVE： To observe the curative effect on duodenal ulcer by pantoprazole treatment. METHODS： 200 cases with duodenal ulcer were divided into two groups. The observation group（n= 100） was treated by pantoprazole treatment. The control group（n=100） was treated by omeprazole treatment. Observed the efficacy, side effect and inflammatory response. RESULTS： The total effective rate （96.84%） was higher in the observation group than in the control group （85.26%）. The inflammatory respone （20.00%） were lower in the observation group than in the control group （45.98%） after treatment. The side effect were lower in the two group. CONCLUSION： The curative effect is satisfied by pantoprazole treatment in duodenal ulcer.
出处
《中国药房》
CAS
CSCD
北大核心
2010年第8期720-721,共2页
China Pharmacy
关键词
十二指肠溃疡
泮托拉唑
黏膜
炎症
消化道
Duodenal ulcer
Pantoprazole
Mucosa
Inflammatory
Alimental tract
