摘要
目的探讨结节病的临床特点及诊断方法。方法对32例经组织病理学确诊的结节病患者的临床资料进行分析。结果平均发病年龄40.3岁,女性多于男性;呼吸系统症状主要表现为咳嗽、胸闷、气促;肺外表现主要为周围淋巴结肿大、发热、皮肤结节;X线胸片及胸部CT提示双侧肺门肿大27例,单侧肺门肿大3例,纵隔淋巴结肿大28例;血清血管紧张素转化酶(SACE)敏感性68.8%;各种活检方法中,纵隔镜淋巴结活检及外科电视胸腔镜下肺活检阳性率最高。结论结节病临床表现多样而无特异性,尽可能行组织病理学检查明确诊断。
Objective To explore the clinical features and diagnosis of sarcoidosis. Methods Clinical materials of 32 consecutive patients with biopsy-proven sareoidosis were retrospectively analyzed. Results The average age was 40. 3 years, there were more fe- male patients than male. The main symptoms of respiratory system included cough, chest distress and anhelation. Of extrepulmonary presen- tation, the most common was superficial lymphadenhypertrophy, fever and skin manifestation. X-ray and CT examination results were as fol- lows ：bilateral hilar hilifuge was larger than the normal 27 cases, single hilifuge larger than normal 3 cases, mediastinal lymphadenectasis in 28 cases. The sensitivity of serum angiotensin converting enzyme （SACE） was 68. 8%. Both the biopsy of lymphonodus of mediastinum through mediastinoscopy and the lung biopsy by video-assisted thoracoscopic surgery were the better methods for the diagnosis of sarcoidosis. Conclusion The clinical presentation of sareoidosis is varied and nonspecific. Pathological examination should be made for the prevention of missed diagnosis and misdiagnosis.
出处
《临床肺科杂志》
2010年第4期481-483,共3页
Journal of Clinical Pulmonary Medicine
关键词
结节病
肉芽肿
血清血管紧张素转化酶
sarcoidosis
granuloma
serum angiotensin converting enzyme
