摘要
目的重度COPD稳定期吸入沙美特罗/氟替卡松临床分析。方法重度COPD稳定期患者60例随机分为治疗组和对照组。对照组给予常规治疗,(应用氨茶碱、异丙托溴铵等)。治疗组在常规治疗的基础上吸入沙美特罗/氟替卡松(50/250)。在治疗前,治疗后4周、12周、24周测定肺功能。治疗24周后评价呼吸困难缓解情况和运动能力改善状况。结果治疗组在治疗后4周、12周、24周肺功能有明显改善,和对照组相比有显著差异(P<0.05),治疗24周后,两组在活动能力、呼吸困难两方面均有改善,治疗组改善更明显。结论沙美特罗/氟替卡松是稳定期重度COPD患者的一种有效治疗方法。
Objective To observe curative effect for severe chronic obstructive pulmonary disease（COPD） case in stabilization period when inhaling salmeterol and fluticason. Methods 60 severe COPD cases of stabilization period were randomly divided into two groups. The comparative group was given routine treatment including salbutamol,ipratropium and aminophylline. In addition to the routine therapy, the treatment group inhaled salmeterol and fluticason（50/250 ）. The pulmonary functions were observed before the treatment, and 4 weeks, 12 weeks ,24 weeks after the treatment. The activity ability and the degree of dyspnea were observed at 24 weeks after the treatment. Results The pulmonary functions of the treatment group improved by the end of 4 week, 12 week and 24 week. The significant differences were seen between the treatment group and the comparative group. The activity ability and degree of dyspnea improved in the two groups. The treatment group had better curative effect than the comparative group. Conclusion The treatment of severe COPD cases in the stabilization period inhaling salmeterol and fluticason is effective.
出处
《临床肺科杂志》
2010年第4期474-475,共2页
Journal of Clinical Pulmonary Medicine
