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妊娠期高血压疾病并发HELLP综合征32例临床分析 被引量:9

A clinical.study of 32 cases with HELLP syndrome
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摘要 目的探讨妊娠期高血压疾病并发HELLP综合征的临床特点及母婴结局。方法对2003年1月至2009年1月收治的32例HELLP综合征患者的临床资料进行回顾性分析。结果HELLP综合征占同期妊娠期高血压疾病的3.7%,其中完全性17例,部分性15例;孕产妇死亡2例(颅内出血1例,急性左心功能衰竭1例),病死率为6.3%,围生儿死亡5例,病死率为15.6%,孕产妇并发症主要为DIE8例(25.0%),胎盘早剥2例,颅内出血2例;新生儿并发症主要为早产20例,新生儿青紫窒息17例,低体质量儿15例。结论HELLP综合征是产科严重的并发症之一,早期诊断,早期治疗,及时终止妊娠是处理的关键。 Objective To analyze the clinical presentation and maternal-neonatal outcome of HELLP syndrome. Methods 32 cases with HELLP syndrome from January 2003 to January 2009 were analyzed retrospectively. Results The incidence of HELLP syndrome in preeclampsia was 3.7%. Complete HELLP were 17 cases, partial HELLP were 15 eases. Two pregnant women died( one case of intracranial hemorrhage ,one ease of acute left cardiac failure) ,the mortality was 6. 3%. Five newborns died ,the mortality was 15.6%. The main materal complications were DIC(8 cases), placental abruption( 2 cases), intracranial hemorrhage (2 eases). The main pefinatal complications were preterm labor(20 cases) ,newborn asphysia( 17 cases) ,SGA( 15 eases). Conclusion HELLP syndrome is one of tbc most serious obstetric complications, early diagnosis, early therapy, controlling hypertension and termination of pregnancy in time are most important for treatment.
出处 《中国基层医药》 CAS 2010年第2期168-169,共2页 Chinese Journal of Primary Medicine and Pharmacy
关键词 高血压 妊娠性 HELLP综合征 临床分析 Hypertension, pregnancy HELLP Syndrome
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参考文献12

  • 1Weinstein L. Syndrome of hemolysis, elevated liver enzymes, and low platelet count. A severe comsequence of hyperpertension in pregnancy. Am J Qbstet Gynecol, 1982,142 ( 2 ) : 159.
  • 2Egerman RS,Sibai BM. HELLP syndrome. Clin Obstet Gynecol, 1999,42 (3) :381-389.
  • 3Pridjian G, Puschett JB. Preeclampsia. Part 1 :Clinical and pathophysiologic considerations. Obstet Gynecol Surv, 2002,57 (9) : 598-618.
  • 4Sullivan CA,Magann EF,Perry KG,et al. The recurrence risk of the syndrome of hemolysis, elevated liver enzymes, and low platelets(HELLP) in subsequent gestations. Am J Obstet Gynecol, 2004,171 (6) :940-943.
  • 5王月玲,苟文丽.HELLP综合征的发病机制及诊治[J].中国实用妇科与产科杂志,2004,20(5):262-264. 被引量:82
  • 6Magann EF,Chauhan SP, Naef R.W,et al. Standard parameters of preeclampsia:can the clinician depend upon them to reliably identify the patient with the HELLP syndrome. Aust NZJ Obstet Gynaecol,2000,33 (2) :122-126.
  • 7Sibai BM. Dignosis, controversies and management of the syndrome of hemolysis, elevated liver enzymes, and low platelet count. Obslet Gynecol,2004,103 (5part 1 ) :981-991.
  • 8O' Brien JM, Barton JR. Controversies with the diagnosis and management of HELLP syndrome. Clin Obstet Gynecol, 2005,48 (2) :460.
  • 9Magann EF, Martin JN. Twelve steps to optimal management of HELLP syndrome. Clin Obstet Gynecol, 1999,42 (3) :532-550.
  • 10Roussillon E, Estrade JP, Guyon F, et al. Importance of thrombocytopcnia for the management of HELLP syndrome: a report of 104 cases. J Gynecol Obstet Biol Reprod ( Paris ) , 2003,32 ( 6 ) : 541-548.

二级参考文献6

  • 1Bussen S, Sutterlin M, Steck T. Plasma endothelin and big endothelin level in women with severe preeclampsia or HELLP-syndrome.Arch Gynecol Obstet, 1999,262 (3-4): 113-119
  • 2Ibdah J A, Yang Z, Bennett MJ. Liver disease in pregnancy and fetal acid oxidation defects. Mol Genet Metab, 2000,71 (1-2): 182-189
  • 3Trmura T, Goldenbery RL, Johnston KE, et al. Serum leptin concentration during pregnancy and their relationship to fetal growth.Obstet Gynecol, 1998,91(3) :389-395
  • 4Bozzo M, Carpani G, Leo L, et al. HELLP syndrome and factor V Leiden. Eur J Obstet Repord Biol, 2001,95 (1) : 55-58
  • 5Martin JN, Files JC, Blake PG, et al. Postpartum plasma exchange for atypical preeclampsia-eclampsia as HELLP. Am J Obstet Gynecol, 1995,172(4): 1107-1125
  • 6Rath W, Faridi A, Dudenhausen JW. HELLP syndrome. Perinat Med, 2000,28 ( 4 ): 249 -260

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