3[1]Griffin JF,Smalley SR,Jewell W,Paradelo JC,Reymond RD,Hassanein RE,Evans RG.Patterns of failure after curative resection of pancreatic carcinoma.Cancer 1990;66:56-61
4[2]Cameron JL,Crist DW,Sitzmann JV,Hruban RH,Boitnott JK,Seidler AJ,Coleman J.Factors influencing survival after pancreaticoduodenectomy for pancreatic cancer.Am J Surg 1991;161:120-124;discussion 124-125
5[3]AI-Hajj M,Clarke MF.Self-renewal and solid tumor stem cells.Oncogene 2004;23:7274-7282
6[4]Bonnet D,Dick JE.Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell.Nat Med 1997;3:730-727
7[5]AI-Hajj M,Wicha MS,Benito-Hernandez A,Morrison SJ,Clarke MF.Prospective identification of tumorigenic breast cancer cells.Proc Natl Acad Sci USA 2003;100:3983-3988
8[6]Singh SK,Hawkins C,Clarke ID,Squire JA,Bayani J,Hide T,Henkelman RM,Cusimano MD,Dirks PB.Identification of human brain tumour initiating cells.Nature 2004;432:396-401
9[7]Collins AT,Berry PA,Hyde C,Stower MJ,Maitland NJ.Prospective identification of tumorigenic prostate cancer stem cells.Cancer Res 2005;65:10946-10951
10[8]Kim CF,Jackson EL,Woolfenden AE,Lawrence S,Babar I,Vogel S,Crowley D,Bronson RT,Jacks T.Identification of bronchioalveolar stem cells in normal lung and lung cancer.Cell 2005;121:823-835
2Wang Y K, Huang Z Q. Protective effects of icariin on human umbilical vein endothelial cell injury induced by H2Oz invitro[J]. Pharmacological Research, 2005, 52:1-174.
3Mackillop WJ, Ciampi A, Till JE, et al. A stem cell model of human tumor growth: implications for tumor cell clonogenic as- says[J]. Nat Cancer Inst, 1983, 70(1) : 9-16.
4Pim D, Massimi P, Dilworth SM, et al. Activation of the protein kinase B pathway by the HPV-16 E7 oncoprotein occurs through a mechanism involving interaction with PP2A [ J ]. Oncogene, 2005, 24(53) : 7830-7838.
5Clayton S, Mousa SA. Therapeutics formulated to target cancer stem cells: Is it in our future? [J] Cancer Cell Int, 2011, 11 : 7.
6Tang C, Ang BT, Pervaiz S. Cancer stem cell: target for anti- cancer therapy [ J ]. FASEB 3, 2007, 21 (14) :3777-3785.
7ten Care B, de Bruyn M, Wei Y, et al. Targeted elimination of leukemia stem ceils; a new therapeutic approach in hemato-on- cology[J]. Curr Drug Targets, 2010, 11(i) : 95-110.
8Li C, I-Ieidt DG, Dalerba P, et al. Identification of pancreatic cancer stem cells[ J]. Cancer Res, 2007, 67(3) : 1030-1037.
9Yang ZF, Ho DW, Ng MN, et al. Significance of CD90 + cancer stem cells in human liver cancer[J]. Cancer Cell, 2008, 13 (2) : 153-166.
10Suetsugu A, Nagaki M, Aoki H, et al. Characterization of CD133 + hepatoceUular carcinoma ceils as cancer stem/progenitor cells [ J]. Biochem Biophys Res Commun, 2006, 351 (4) : 820-824.
