摘要
通过一条新路线合成了2-(2-羟基苯基)苯并咪唑异硫氰酸酯,对反应条件进行优化,得出较佳反应条件,收率为78.7%.产物通过核磁、红外光谱对其结构进行表征.该路线适合水溶性不好的物质异硫氰酸酯化,进一步拓宽了二硫化碳/重金属盐法在合成异硫氰酸酯中的应用范围.另外,这条路线的整个合成过程,在低于5℃条件下进行,适合合成一些带有活性基团的复杂异硫氰酸酯.
2-（2-hydroxyphenyl ）benzazole isothiocyanate was synthesized and a new route was created yield 78.7%. Its structure was characterized by ^1H NMR and IR. The reaction condition was below 5℃. It was suitable to water insoluble compounds and materials with active functional groups. The method concluding carbon disulphide and heavy metallic salt can be used extensively in the synthesis of isothiocyanates.
出处
《天津理工大学学报》
2010年第1期5-7,共3页
Journal of Tianjin University of Technology
基金
国家自然科学基金(20771082)
天津市自然科学基金(09JCYBJC05800)
关键词
异硫氰酸酯
二硫化碳
重金属盐
合成
isothiocyanates
carbon disulphide
heavy metallic salt
synthesis
