期刊文献+

替米沙坦对老年高血压患者左室肥厚和胰岛素抵抗的影响 被引量:1

暂未订购
导出
摘要 【目的】探讨替米沙坦治疗老年高血压患者对其左室肥厚及胰岛素抵抗的影响。【方法】对36例高血压病患者接受替米沙坦降压治疗24周后,治疗前后检测空腹及餐后2h血糖、胰岛素值,计算胰岛素敏感性指数,进行超声心动图检查。【结果】替米沙坦能够显著降低患者血压,提高胰岛素敏感指数(P〈0.01),室间隔厚度、左心室后壁厚度、左室心肌重量及左室重量指数较治疗前显著改善(P〈0.01)。【结论】替米沙坦在降压的同时,具有改善其胰岛素抵抗和左心室肥厚的作用。
作者 刘中健
出处 《医学临床研究》 CAS 2010年第2期338-339,共2页 Journal of Clinical Research
  • 相关文献

参考文献9

  • 1Poeh E, Giner V, Nunez DG, et al . Association of the Gprotein β2 subunit T alele with insulin resistance in essential hypertension[J]. Clin Exp Hyperten ,2002,24 (3) :345-353.
  • 2Mancia G. The association of hypertension and diabetes prevalence, cardiovascular risk and protection by Blood pressure reduction[J]. Acta Diabetol ,2005,42(suppl 1): S17-25.
  • 3戴小良,刘小雨,王行宽.高血压左室肥厚与胰岛素抵抗的研究进展[J].医学综述,2006,12(14):847-849. 被引量:5
  • 4Benson SC, Pershadsingh HA, Ho CI, a al . Identification of telmisartan as a unique angiotensin receptor antagonist with selective PPARγ-modulating activity[J]. Hypertension , 2004,43 (5) :993-1002.
  • 5Galzerano D, Tammaro P, Cerciello A, et al . Freehand three- dimensional echocardiographic evaluation of the effect of telmisartive of the effect of telmisartan compared with hydrochlorothiazide on left ventricular mass in hypertensive patients with mild-to-moderate hypertension: a multicentre study [J]. J Hum Hypertens ,2004,18 (1) :53-59.
  • 6Kothari K. A study of the influence of insulin resistance on left wentricular mass in hypertensive patients [J ]. J Assoc Physicians India ,2000,48(3) : 279-283.
  • 7郭旭梅,马淑平,陈步星,罗维.胰岛素抵抗的肾素依赖性高血压大鼠左室肥厚的实验研究[J].中国医药导刊,2006,8(1):58-60. 被引量:1
  • 8李光伟,李光伟.高血压与糖尿病-代谢综合症的两柄利剑[J].高血压杂志,2003,11(1):3-4. 被引量:49
  • 9Rosano G, Vitale C, Castiglioni C, et al . Comparative effects of telmisartan and losartan on glucose metabolism in hypertensive patients with 'the metabolic syndrome [J]. Scientific Session American Heart Association , 2004 New Orleans.

二级参考文献31

  • 1李光伟,张辉,潘孝仁,胡英华,王继兴,萧建中,李进平,胡泽溪,王金平.原发性高血压为Ⅱ型糖尿病发病独立预测因素──非糖尿病人群465例6年前瞻性观察[J].中华内科杂志,1994,33(10):654-657. 被引量:48
  • 2胡英华,李光伟,姜亚云,王继兴,姜锡贵,胡泽溪,潘孝仁.新诊NIDDM人群中血浆胰岛素水平与血压的相关性[J].中华内分泌代谢杂志,1995,11(4):211-213. 被引量:8
  • 3卜培莉 王淑贞 张运 等.高血压病患者血清胰岛素样生长因子与左室肥厚的关系[J].中华心血管病杂志,2000,28(3):184-184.
  • 4Poch E, Giner V, Nunez DG, et al. Association of the G protein β2 subunit T alele with insulin resistance in essential hypertension [J]. Clin Exp Hyperten,2002,24(3):345-353.
  • 5Miyazato J, Horio T, takishita S, et al. Fasting plasma glucose is an independent determinent of left ventricular diastolic dysfunction in nondiabetic patients with essential hypertension[J]. Hypertens Res,2002,25(3) :403-409.
  • 6Sundstrom J, Lind L, Nystrom N, et al. Left ventricular concentric remodeling rather than left ventricular hypertrophy is related to the insulin syndrome in elderly men[J]. Circulation,2000,101(22):2595-2600.
  • 7Fiordaliso F, Li B, Latini R, et al. Myocyte death in streptozotoc in induced diabetes in rats is angiotens in 11-dependent[J]. Lab Invest,2000,80(6) :513.
  • 8Defronzo RA. The effect of insulin on renal sodium metabolic syndrome[ J]. J Hypertens, 1995,13:433.
  • 9Kamide K, Rakugi H, Higaki J, et al. The renin-angiotensin and adrenergic nervous system in cardiac hypertrophy in fructose-fed rats[J]. Am J Hypertens,2002,15(1 Pt 1):66-71.
  • 10Kothari K, Devpura G, Sharma A, et al. A study of the inflience of insulin resistance on left ventricular mass in hypertinsive patients [ J ]. J Assoc Physicians India,2000,48(3):279-283.

共引文献52

同被引文献5

二级引证文献1

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部