摘要
目的评价血管紧张素转换酶抑制剂(ACEI)喹那普利对原发性高血压患者心率变异性(HRV)的影响。方法选择原发性高血压患者32例,分别记录喹那普利治疗4周前后24h动态心电图,进行心率变异性的时域分析和频域分析,并与对照组进行比较。结果原发性高血压组与对照组比较心率变异性降低,经喹那普利治疗后,原发性高血压组血压下降的同时心率变异性指标均显著改善。结论喹那普利可以改善原发性高血压患者的心率变异性。
Objective To evaluate the effect of Quinapril on heart rate variablility（HRV） in essential hypertensive patients.Methods The data of HRV were analyzed in 32 healthy subjects and 32 patients with hypertension before and after using quinapril by 24-hour ambulatory electrocardiographic recordings.Results The data of HRV,such as standard deviation of nomal-to-nomal intervals（SDNN）,standard deviation of the mean of RR intervals for each 5 periods of the 24-hour ambulatory electrocardiographic recordings（SDANN）,total frequency low frequency and high frequency in hypertensive patients were significantly abnormal compared with that in control.After treatment of Quinapril,HRV were significantly improved.Conclusion Quinapril can improve the HRV of essential hypertensive patients.
出处
《医药论坛杂志》
2010年第1期36-37,40,共3页
Journal of Medical Forum
