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高危型人乳头瘤病毒检测联合液基薄层细胞学检查在宫颈癌筛查中的临床价值 被引量:18

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摘要 目的探讨高危型人乳头瘤病毒(HPV-DNA)检测联合液基薄层细胞学检查(TCT)用于宫颈癌筛查的临床价值。方法2006年1月至2009年6月在我院接受筛查的妇女1652例随机分两组(即TCT组及HPV-DNA+TCT组)。TCT组822例,HPV-DNA+TCT组830例,分别进行TCT检查及高危型HPV杂交捕获法二代检查(HC2)+TCT,同时检查比较两组阳性病例与病理检查结果的阳性符合率。结果TCT组822例中检出TCT阳性96例,占11.68%,病理检查结果阳性66例,阳性符合率为68.75%;HPV-DNA+TCT组830例中检出高危型HPV与TCT同时阳性者58例,占6.99%,病理检查结果阳性55例,阳性符合率为94.83%;两组与病理检查的阳性符合率比较,差异显著(P<0.05)。结论HPV-DNAHC2联合TCT与病理检查的阳性符合率明显高于单纯TCT,用于宫颈癌筛查准确性高,漏诊率低。
作者 王方
出处 《临床和实验医学杂志》 2010年第6期443-444,共2页 Journal of Clinical and Experimental Medicine
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