摘要
目的了解住院患者下呼吸道感染病原菌的分布及耐药特点,为临床合理用药提供依据。方法对2006年至2008年住院患者下呼吸道感染痰标本所分离的病原菌,进行菌种和耐药性回顾性统计分析。结果临床所分离的1732株病原菌中,前几位依次为铜绿假单胞菌、鲍曼不动杆菌、肺炎克雷伯菌、大肠埃希菌、白色念珠菌、阴沟肠杆菌、产碱假单胞菌和嗜麦芽假单胞,对抗菌药物耐药率普遍较高的细菌为铜绿假单胞菌和产碱假单胞菌。结论下呼吸道感染病原菌以革兰阴性杆菌为主,临床应合理应用抗菌药物,以延缓细菌耐药性的产生。
Objective To investigate the distribution and antibiotie resistance of pathogens isolated from nosoeomial lower respiratory tract infection for rational antimierobial therapy. Methods A retrospective analysis for the antibiotic resistance of pathogen isolated from sputum sample of nosoeomial lower respiratory tract infection was mede in our hospital from 2006 to 2008. Results 1 732 clinical isolates, the outstanding pathogens were Pseudomonas aeruginosa, Aeinetobaeter baumannii, Klebsiella pneumoniae, Escheriehia eoli, Candida albicans, Enterobaetor cloacae, Pseudomonas alealigenes, and Stenotrophomonas mahophilia. The resitant rate was higher in Pseudomanas aeruginosa, Pseudomanas alealigenes. Conclusion Gramnegative bacilli are the major pathogens in nosoeomial lower respiratory traet infection antibiotic resistance becomes more prevalent in some major pathogens. Rational use of antibiotics is important for the containment of bacterial resistance.
出处
《临床和实验医学杂志》
2010年第6期419-420,423,共3页
Journal of Clinical and Experimental Medicine
关键词
下呼吸道感染
住院患者
病原菌
耐药性
Lower respiratory tract infeetian
Inpatients
Pathogen
Drug resistance
