摘要
目的比较经皮椎体成形术(PVP)与经皮椎体后凸成形术(PKP)在治疗骨质疏松性椎体压缩性骨折方面的疗效。方法本科近一年收治的42例骨质疏松性椎体压缩性骨折患者,按家属意愿分别实施PVP(24例,37椎体)、PKP(18例,29椎体)治疗。分别于术前、术后1周及术后6月用疼痛强度视觉类比评分(VAS)对患者疼痛程度进行评估,并通过影像学检查评估Cobb角矫正程度及骨水泥渗漏发生率。结果42例手术均成功完成。无论是PVP组还是PKP组,VAS评分术后1周及术后6月均较术前明显改善(P<0.05),术后6月评分较术后1周评分无统计学差异(P>0.05)。PKP组与PVP组相比,术后6月与术前的VAS评分的改善情况无显著性差异(P>0.05)。术后PVP组和PKP组Cobb角均有明显改善(P<0.05),并且PKP组较PVP组更明显(P<0.05)。并发症的发生率PVP组为20.8%(5例出现椎体周围骨水泥渗漏);PKP组为11.1%(2例出现椎体周围骨水泥渗漏,无一例出现肺栓塞),两组比较差异有显著性(P<0.05)。结论PVP与PKP均可显著缓解骨质疏松性椎体压缩性骨折患者的疼痛;但是PKP较PVP有更高的畸形矫正率,更低的并发症发生率,对于骨质疏松性椎体压缩性骨折来说,是一种更有效的手术方式。
Objective To compare the clinical efficacy between percutancous vertebroplasty （PVP） and percutaneous kyphoplasty （PKP） in the treatment of vertebral osteoporotie compression fracture （OVCF）. Methods Forty - two patients with vertebral osteoporotic compression fracture （OVCF） were followed up last year. Among them, 24 patients （37 vertebral bodies） treated with PVP, 18 patients （29 vertebral bodies） treated with PKP. Each patient was followed up for 6 months. The level of pain were measured with visual analogue pain scale （VAS） ,the Cobb angle of preoperatively and postoperatively and the incidence rate of complication between the two groups were compared. Results The VAS score of postoperatively were decreased obviously compared with preoperative （ P 〈 0.05 ）, but there was no significant difference between the two groups （ P 〉 0.05 ）. The Cobb angle was obviously smaller than preoperatively in the two groups （ P 〈 0.05 ） ; and statistical difference was noted between the two groups （ P 〈 0.05 ）. The incidence rate of complication in PVP group was 20.8% （4 cases bone cement leakage） , significantly higher than 11.1% （2 cases bone cement leakage） in PKP group. Conclusion Both PVP and PKP can quickly relieve pain and enhance vertebral stability in patients with OVCF, but PKP is more efficient method in correcting deformity and decreasing the incidence rate of complication.
出处
《临床和实验医学杂志》
2010年第6期415-417,共3页
Journal of Clinical and Experimental Medicine
