冠状动脉狭窄程度与急性心肌梗死被引量：1

Relation between coronary arterial stenosis and acute myocardial infarction

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摘要目的研究急性心肌梗死（AMI）患者梗死相关冠状动脉的狭窄程度。方法对171例AMI患者进行回顾性分析，所选患者须满足：①经过充分的抗栓药物治疗；②接受造影的时间为AMI发生后6～30d；③行球囊扩张前恢复梗死相关动脉的前向血流。通过定量冠状动脉造影（QCA）评价管腔狭窄程度，比较分析各主要分支之间的差异。结果171例患者中病变血管中、重度狭窄者（〉50％）161例，占94．15％，而单纯重度狭窄者（〉70％）160例，占93．57％。前降支（LAD）、回旋支（LCX）与右冠状动脉（RCA）平均直径狭窄百分数分别为（84±21）％、（82±31）％、（81±32）％，三者之间差异无统计学意义（P均〉0．05）。结论绝大多数AMI是在中、重度冠状动脉狭窄的基础上发生的。 Objective To assess the underlying stenosis severity of the culprit lesion in patients with acute myocardial infarction （AMI）. Methods 171 patients with AMI were analyzed retrospectively and the following criteria were met： ① patients were treated with adequate antithrombotic drugs; ② angiography was performed within 6-30 days after the onset of symptoms of AMI ; ③infarct related artery flow recovered before balloon expansion. Quantitative coronary angiography （QCA） was performed to estimate the stenosis severity and the differences of stenosis severity in the main branches were analyzed. Results In 171 patients, 161 patients （94.15%） showed moderate and severe stenosis （coronary artery diameter stenosis percentage more than 50% ）, while 160 patients （93.57%） showed severe coronary stenosis （coronary artery diameter stenosis percentage more than 70% ）. The average diameter stenosis percentage of the left anterior descending （ LAD）, left circumflex （LCX） and right coronary artery （RCA） were （ 84 ± 21 ） %, （ 82 ± 31 ） % and （ 81 ± 32 ） % respectively, and there were no significant differences among them （ P 〉 0.05 ）. Conclusion The majority of acute myocardial infarctions occur in moderate and severe coronary stenosis.

作者李琳陈良华宋尚明衣少雷刘同宝

机构地区山东大学附属省立医院心内科

出处《山东大学学报（医学版）》 CAS 北大核心 2010年第2期117-120,共4页 Journal of Shandong University:Health Sciences

关键词心肌梗死冠状动脉造影狭窄 Myocardial infarction Angioplasty Coronary stenosis

分类号 R541.4 [医药卫生—心血管疾病]

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