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肥胖与高密度脂蛋白代谢异常研究进展 被引量:3

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摘要 肥胖是代谢综合征发生发展的中心环节,其与代谢综合征的各个危险因素密切相关。高密度脂蛋白胆固醇水平降低是代谢综合征的特征性血脂代谢异常之一。有研究表明肥胖可通过多种途径影响体内高密度脂蛋白水平和功能,如高甘油三酯血症,脂肪细胞因子,炎症状态,载脂蛋白M异常等。而高密度脂蛋白胆固醇水平降低及功能异常是动脉粥样硬化进展的独立危险因素。本文就肥胖与高密度脂蛋白异常及其影响因素的研究进展作一综述。
出处 《中国动脉硬化杂志》 CAS CSCD 北大核心 2009年第12期1041-1044,共4页 Chinese Journal of Arteriosclerosis
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  • 1Call AM, Zern TL, Taksali SE, et al. Intrahepatic fat accumulation and alterations in lipoprotein cornpoeition in obese adolescents: a perfect proatherogenie state [ J ]. Diabetes Care, 2007, 30 (12) : 3 093 -098.
  • 2陈少敏,郭丽君,高炜.高密度脂蛋白胆固醇对冠状动脉粥样硬化的影响[J].临床心血管病杂志,2008,24(3):223-225. 被引量:18
  • 3Howard BV, Ruotolo G & Robbins DC. Obesity and dyslipidemia [ J ]. J Chin Endocr Metab, 2003, 32 (4) : 855-867.
  • 4刘静,赵冬,刘军,刘飒,秦兰萍,吴兆苏.代谢综合征与自由脂肪酸的关系[J].中华心血管病杂志,2005,33(7):653-657. 被引量:12
  • 5Lewis GF, Bader DJ. New insights into the regulation of HDL metabolism and reverse cholesterol transport [ J]. Circ Res, 2005, 96 (12) : 1 221- 232.
  • 6Xiao Changhng, Takehiko Watanabe, Zhang Yi, et al. Enhanced cellular uptake of remnant high-density Iipoprotein particles a mechanism for highdensity Iipopvoteln lowering in insulin resistance and hypertriglyceridemia [J].Circ ReJ, 2008, 103 (2) : 159-166.
  • 7Watts GF, Barrett PHR, Ji J, et al. Differential regulation of lipoprotein kinetics by atorvastatin and fenofibrate in subjects with the metabolic syn- drome [J]. Diabetes, 2003, 52 (3) : 803-811.
  • 8Chan DC, Nguyen MN, Watts GF, et aL Plasma apolipoprotein C-Ill transport in centrally obese men: associations with very low-density lipoprorein apolipoprotein B and high-density lipoprotein apolipoprotein A-I metab- dlsm [J]. J Clin Endocr Mew.b, 2008, 93 (2) : 557-564.
  • 9Adieh M, Taskinen MR, Packard C, et al. Overproduction of large VLDL particles is driven by increased liver fat content in man [J].D/abets, 2006, 49 (4) : 755-765.
  • 10Fabbrini E, Mohammed BS, Magkos F, et al. Alterations in adipose tissue and hepatic lipid kinetics in obese men and women with nonalcoholic fatty liver disease [J]. C, astroenter, 2008, 134 (2) : 424-431.

二级参考文献17

  • 1谭小进,王岳林.冠心病患者心电图ST段水平延长与冠状动脉狭窄程度的相关性及诊断价值[J].中国动脉硬化杂志,2004,12(6):710-712. 被引量:12
  • 2荆朝辉,张晓膺,NING Xu,罗光华,董选.2型糖尿病患者中载脂蛋白M与脂蛋白a、载脂蛋白AI的关系研究[J].现代医学,2006,34(2):96-100. 被引量:11
  • 3甘润韬,李为民,李竹琴,王岚峰.超敏C反应蛋白及血脂水平与急性冠状动脉综合征患者6个月内预后的关系[J].临床心血管病杂志,2006,22(11):650-652. 被引量:6
  • 4CHOBANIAN A V, BAKRIS G L, BLACK H R, et al. The seventh report of the joint national committee on prevention, detection, evaluation, and treatment of high blood pressure: the JNC 7 report[J]. JAMA, 2003, 289:2560-2572.
  • 5Executive summary of the third report of the national cholesterol education program (NCEP) expert panel on detection, evaluation, and treatment of high blood cholesterol in adults (adult treatment panel Ⅲ) [J]. JAMA, 2001, 285: 2486-2497.
  • 6American diabetes association. Standards of medical care in diabetes[J]. Diabetes Care, 2005, 28:S4 - 36.
  • 7MILLER M, SEIDLER A, KWITEROVICH P, et al. Long-term predictors of subsequent cardiovascular events with coronary artery disease and 'desirable' levels of plasma total cholesterol [J]. Circulation, 1992, 86: 1165-1170.
  • 8JOHNSEN S H, MATHIESEN E B, FOSSE E, etal. Elevated high-density lipoprotein cholesterol levels are protective against plaque progression: a follow-up study of 1952 persons with carotid atherosclerosis the tromso study[J]. Circulation, 2005, 112: 498-504.
  • 9ELLISON R C, ZHANG Y, QURESHI M M, et al. Life style determinants of high-density lipoprotein cholesterol: the national heart, lung, and blood institute family heart study[J]. Am Heart J, 2004,147: 529-535.
  • 10Bjom Dahlback, Lars B, Nielsen. Apolipoprotein M: a nover player in high- density lipoprotein metabolism and atherosclerosis [J]. Curr Opin Lipidol, 2006, 17 (3): 291-295.

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  • 1Baigent C, Blackwell L, Emberson J, et al. Efficacy and safety of more intensive lowering of LDL cholesterol: a meta-analysis of data from 170, 000 participants in 26 ran- domised trials [ J ]. Lancet, 2010, 376 (9753) : 1 670-681.
  • 2Carey VJ, Bishop L, Laranjo N, et al. Contribution of high plasma triglycerides and low high-density lipoprotein cholesterol to residual risk of coronary heart disease after establishment of low-density lipoprotein cholesterol control [ J ]. Am J Cardiol, 2010, 106 (6) : 757-763.
  • 3Barter P, Gotto AM, LaRosa JC, et al. HDL cholesterol, very low levels of LDL cholesterol, and cardiovascular disease [J]. N Engl J Med, 2007, 357 (13) : 1301-310.
  • 4Chapman M J, Ginsberg HN, Amarenco P, et al. The European Atherosclerosis Society Consensus Panel. Triglyceride-rich lipoproteins and high-density lipoprotein cholesterol in patients at high risk of cardiovascular disease: evidence and guidance for management [J]. Eur Heart J, 2011, 32 ( 11 ) : 1 345-361.
  • 5Gordon T, Castelli WP, Hjortland MC, et al. High density lipoprotein as a protective factor against coronary heart disease. The Framingham Study [J]. Am J Med, 1977, 62 (5) : 707-714.
  • 6Ridker PM, Genest J, Boekholdt SM, et al. JUPITER Study Group. HDL cholesterol and residual risk of first cardiovascular events after treatment with potent statin thera- py: an analysis from the JUPITER trial [ J ]. Lancet, 2010, 376 (9738): 333-339.
  • 7Singh IMp Shishehbor MH, Ansell BJ. High-density lipoprotein as a therapeutic target: a systematic review [ J ]. JAMA, 2007, 298 (7): 786-798.
  • 8Briel M, Ferreira-Gonzalez I, You JJ, et al. Association between change in high density lipoprotein cholesterol and cardiovascular disease morbidity and mortality: systematic review and meta-regression analysis [ J ]. BMJ, 2009, 338 : b92.
  • 9Armitage J. The safety of statins in clinical practice [ J ]. Lancet, 2007, 370 (9601): 1 781-790.
  • 10Genest J, McPherson R, Frohlich J, et al. 2009 Canadian Cardiovascular Society/Canadian guidelines for the diagnosis and treatment of dyslipidemia and prevention of cardiovascular disease in the adult 2009 recommendations [J]. Can J Cardiol, 2009, 25 (10): 567-579.

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