摘要
目的:观察富血小板纤维蛋白的显微和超微结构并探讨其相关生物学特性。方法:实验组6名健康志愿者,随机分为3组,采取肘静脉全血制备6份PRF标本,分别行光镜、SEM和TEM观察。采集对照组2名志愿者静脉全血制备PRP进行SEM观察。结果:PRF中纤维蛋白聚集形成疏松的立体网络结构,大量的血小板和白细胞分布于纤维蛋白网中,血小板内α颗粒部分破裂。PRP中血小板伸出大量的伪足并且聚集成簇相互堆叠,少量白细胞散在。结论:PRF的纤维蛋白网状结构是其相对延长生长因子作用时间的结构基础,所含的大量白细胞可能具有很高的免疫学价值。
Objective： To observe microstructure and uhrastructure of platelet--rich fibrin and to investigate its potential biological characteristics. Methods： In the experimental group 6 healthy donors were randomly divided into 3 groups. Whole blood was collected from them to prepare PRF, and then samples were observed by optical microscope, SEM and TEM. Two donors＇ whole blood in control group was collected to prepare PRP, and then the sam- ples were observed by SEM. Results： In PRF, fibrins get together for a porous three--dimensional network structure, lots of platelets and leucocytes were trapped in the fibrin net structure, and some a--granules in platelet were broken. In PRP platelets spread lots of pseudo pods and accumulated in a big cluster, a little leucocytes scat- ter. Conclusion： Fibrin network structure of PRF is the main structural foundation for prolonging the effect of cyto- kines. Lots of leucocytes in PRF may have plenty of immunological value.
出处
《口腔医学研究》
CAS
CSCD
北大核心
2010年第1期98-101,共4页
Journal of Oral Science Research
基金
天津市教委科技基金资助项目(编号:20060113)
关键词
富血小板纤维蛋白
富血小板血浆
扫描电镜
透射电镜
Platelet--rich fibrin Platelet--rich plasma Scanning electron microscope Transmit electron microscope
