摘要
可吸收骨折内固定材料要求具有很好的组织相容性。本文将自行研制的可吸收羟基磷灰石／聚ＤＬ乳酸（ＨＡ／ＰＤＬＬＡ）内固定材料植入兔肌肉和骨组织中，于３、６、１２、２４、３６、５２周取材，作ｘ线摄片和组织学观察。结果：骨折在６周内正常愈合，５２周内组织反应较轻，无大量炎性细胞集聚。结论：ＨＡ／ＰＤＬＬＡ复合材料具有很好的组织相容性。
The long term tissue compatibility of self designed hydroxyapatite/poly(DL Lactide) (HA/PDLLA) fracture fixation devices were investigated in muscle or concellous bone in 30 rabbits.The follow up times were three, six, 12,24,36 and 52 weeks.Roentgenographic and histologic studies were done.The results showed that all osteotomies united within six weeks without delay.The tissue reaction was mild within 52 weeks for there was no accumulation of inflammatory cells.Consequently,The HA/PDLLA composites possess good tissue compatibiltity.
基金
湖北省科技攻关项目资助
