摘要
大肠癌肝转移过程包括了肿瘤细胞的浸润,在血液循环中的生存,进入肝脏并进行增殖;此过程涉及一系列的分子标记,其中血管内皮生长因子和表皮生长因子受体是临床靶向治疗的主要的分子靶点。
The process of liver metastasis of colorectal cancer includes tumor cells invasion, survival in blood stream, extravasation to the liver and proliferation. It is involved in series of molecular markers, among which vascular endothelial growth factor and endothelial growth factor receptor are the major targets.
出处
《国际肿瘤学杂志》
CAS
2009年第12期940-943,共4页
Journal of International Oncology
关键词
结直肠肿瘤
肿瘤转移
肿瘤标记
生物学
Colorectal neoplasms
Neoplasm metastasis
Tumor markers, biological