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甲状腺癌分子影像诊断与靶向治疗研究进展 被引量:4

Advances on molecular imaging diagnosis and targeted therapy of thyroid cancer
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摘要 甲状腺癌是内分泌系统最常见的肿瘤之一,医学影像学检查是甲状腺癌诊断及预后评价的主要方法。近年来,分子影像学作为一门新兴学科,在活体状态下通过影像学手段定性和定量显示甲状腺癌在细胞和分子水平的特定分子表达及其水平变化等方面取得了明显进展。该文综述了国内外有关甲状腺癌分子影像诊断及分子靶向治疗方面的最新进展。 Thyroid cancer is one of the most common endocrine tumors. Medical imaging examinations play a major role in diagnosing thyroid carcinoma and evaluating its therapeutic response. Recently, molecular imaging, as an emerging discipline, has made significant progress in qualitatively and quantitatively demonstrating the specific molecular alteration of thyroid cancer in cellular and molecular levels in vivo. This article is a summary of the advances on the molecular imaging diagnosis and the targeted therapy of thyroid cancer at home and abroad.
作者 常伟 高再荣
出处 《国际放射医学核医学杂志》 2009年第4期218-221,共4页 International Journal of Radiation Medicine and Nuclear Medicine
基金 卫生部部属(管)医院临床学科重点项目(卫规财函[2007]353号)
关键词 甲状腺肿瘤 分子诊断技术 发射型计算机 体层摄影术 放射疗法 Thyroid neoplasms Molecular diaghostic techniques Tomography, emission-computed Radiotherapy
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参考文献17

  • 1Weissleder R. Molecular imaging: exploring the next frontier. Radiology, 1999. 212(3): 609-614.
  • 2Bartolazzi A, Orlandi F, Sagiorato E, et al. Galectin-3-expression analysis in the surgical selection of follicular thyroid nodules with indeterminate fine-needle aspiration cytology: a prospective multicentre study. Lancet Oncol, 2008, 9(6): 543-549.
  • 3Bartolazzi A, D'Alessandria C, Parisella MG, et al. Thyroid cancer imaging in vivo by targeting the anti-apoptolic, molecule galectin-3. PLoS One, 2008.3(11): e3768.
  • 4Haslinghuis LM. Krenning EP, De Herder W W, et al. Somatostatin receptor scintigraphy in the follow-up of patients with differentiated thyroid cancer. J Endocrinol Invest. 2001, 24(6): 415-422.
  • 5Giammarile F, Houzard C, Bournaud C. et al. Diagnostic management of suspected metastatic thyroid carcinoma: clinical value of octreotide seintigraphy in patients with negative high-dose radioindine scans, Eur J Endocrinol. 2004, 15013): 277-283.
  • 6Kwekkeboom DJ, Teunissen J J, Bakker WH, et al. Radiolabeled somatostatin analog [^177Lu-DOTA^0,Tyr^3]octreotate in patients with endoerine gastroenteropancreatic tumors. J Clin Oncol. 2005, 23 (12): 2754-2762.
  • 7张浩然,马庆杰,赵劼,高识,孟祥芹,赵国庆.^(131)I-chTNT在分化型甲状腺癌肺转移患者体内的生物学分布[J].中国老年学杂志,2009,29(1):65-67. 被引量:2
  • 8Helal BO. Merlet P, Toubert ME, et al. Clinical impaet of ^18F-FDG PET in thyroid carcinoma patients with elevated thyroglobulin levels and negative ^131I scanning results after therapy. J Nucl Med. 2001.42(10): 1464-1469.
  • 9Petrich T, B rner AR, Otto D, et al. Influence of rhTSH on [^18F] fluorodeoxyglucose uptake by differentiated thyroid carcinoma. Ear J Nuet Med Mol Imaging, 2002, 29(5): 641-647.
  • 10Phan HT, Jager PL, Paans AM, et al. The diagnostic value of ^134I- PET in patients with differentiated thyroid vancer. Eur J Nucl Med Mol Imaging, 2008, 35(5): 958-965.

二级参考文献5

  • 1Nachar O, Rousseau JA, keflbvre B,et al. Biodistribution dosimetry and metabolism of 11 β-methoxy-( 17α, 20E/Z )-( ^123 1 ) iodovinylestradiol in healthy women and breast cancer patients[J]. J Nucl Med,1999;40:1728-36.
  • 2Chen SL, Yu L, Jiang CY, et al. Pivotal study of iodine-131 -labeled chimeric tumor necrosis treatment radioimmunotherapy in patients with advanced lung cancer[ J]. J Oncol,2005 ;23 : 153847.
  • 3Patel SJ, Shapiro WR, Laske DW, et al. Safety and feasibility of convection-enhanced delivery of cotara for the treatment of malignant glioma : initial experience in 51 patients[ J]. Neurosurgery,2005 ;56 : 1243-2353.
  • 4William RS, Susan PC, Roberts K, et al. ^131 I-chTNT-1/BmAb: Tumour necrosis therapy for malignant astrocytic glioma[ J ]. Expert Opin Biol Ther,2006 ;6:539-45.
  • 5Homick JL, Sharifi J, Khawli LA, et al. Single amino acid substitution in the Fc region of chimeric TNT-3 antibody accelerates clearance and improves immunoscintigraghy of solid tumors [ J]. J Nucl Med, 2000;41: 355-62.

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