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特异T细胞免疫与肺癌 被引量：2

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摘要 特异性T细胞免疫是机体抗肿瘤和抗病毒感染等的重要防御能力。在肿瘤患者中，T细胞免疫的强弱与肿瘤的发生发展和预后密切相关，深入了解其细胞免疫特点，对于预测预后和设计相应的免疫治疗方案有重要意义。
作者 李扬秋 吴一龙
机构地区 暨南大学医学院血液病研究所 广东省医学科学院 广东省人民医院肺癌研究所
出处 《癌症进展》 2010年第1期75-79,共5页 Oncology Progress
基金 国家高技术研究发展计划(863计划)(项目编号:2006AA02Z114)
关键词 肺癌 T细胞免疫 T细胞受体
分类号 R730.3 [医药卫生—肿瘤] R734.2 [医药卫生—肿瘤]
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参考文献23

  • 1Korn S, Wiewrodt R, Walz YC, et al. Characterization of the interstitial lung and peripheral blood T cell receptor repertoire in cigarette smokers [ J ]. Am J Respir Cell Mol Biol, 2005, 32 (2):142.
  • 2Echchakir H, Asselin - Paturel C, Dorothee G, et al. Analysis of T - cell - receptor beta - chain - gene usage in peripheral - blood and tumor - infiltrating lymphocytes from human non - small - cell lung carcinomas [ J ]. Int J Cancer, 1999, 81 (2):205.
  • 3周昕熙,李锦添,吴一龙,王思愚,杨学宁,陈诗萍.非小细胞肺癌患者T细胞受体Vβ表达和克隆性研究[J].中国肺癌杂志,2003,6(2):107-110. 被引量：3
  • 4吴一龙,杨学宁,李锦添,王思愚.基因扫描分析非小细胞肺癌病人外周血和骨髓T细胞克隆性增殖及分布特点[J].癌症,2000,19(3):204-207. 被引量：8
  • 5杨学宁,吴一龙,李锦添,王思愚,周昕熙.非小细胞肺癌患者肿瘤浸润性淋巴细胞中T细胞克隆性增殖[J].肿瘤,2000,20(6):396-400. 被引量：1
  • 6Derniame S, Vignaud JM, Faure GC, et al. Comparative T -cell oligoclonality in lung, tumor and lymph nodes in human non - small cell lung cancer [ J ]. Oncol Rep, 2005, 13 (3):509.
  • 7李扬秋,陈少华,杨力建,祁明芳.CML病人TCR Vβ21寡克隆T细胞及其CDR3序列特点[J].免疫学杂志,2000,16(3):189-192. 被引量：21
  • 8Ferrarini M, Hehai S, Chiesa G, et al. V delta 1 + gamma/deha T lymphocytes infiltrating human lung cancer express the CD8 alpha/alpha homodimer [ J ]. Scand J Immunol, 1994, 40 (3) : 363.
  • 9Dorothee G, Vergnon I, E1 Hage F, et al. In situ sensory adaptation of tumor - infiltrating T lymphocytes to peptide - MHC levels elicits strong antitumor reactivity [ J]. J Immunol, 2005, 174 ( 11 ) : 6888.
  • 10Echchakir H, Dorothee G, Vergnon I, et al. Cytotoxic T lymphocytes directed against a tumor - specific mutated antigen display similar HLA tetramer binding but distinct functional avidity and tissue distribution [J]. Proc Natl Acad Sci USA, 2002, 99 (14):9358.

二级参考文献23

  • 1[1]Schumacher K, Haensch W, Roefzaad C, et al. Prognostic significance of activated CD8(+) T cell infiltrations within esophageal carcinomas. Cancer Res,2001,61(10)∶3932-3936.
  • 2[2]Michael-Robinson JM, Biemer-Huttmann A, Purdie DM, et al. Tumour infiltrating lymphocytes and apoptosis are independent features in colorectal cancer stratified according to microsatellite instability status. Gut,2001,48(3)∶360-366.
  • 3[3]Wei YQ(魏于全), Hang ZB. In situ observation of lymphocyte-tumor cell interaction in human lung carcinoma. Immunol Invest,1989,18(9-10)∶1095-1105.
  • 4[4]Maccalli C, Farina C, Sensi M, et al. TCR beta-chain variable region-driven selection and massive expansion of HLA-class I-restri-cted antitumor CTL lines from HLA-A*0201+ melanoma patients. J Immunol,1997,158(12)∶5902-5913.
  • 5[5]Angevin E, Kremer F, Gaudin C, et al. Analysis of T-cell immune response in renal cell carcinoma: polarization to type 1-like differentiation pattern, clonal T-cell expansion and tumor-specific cytotoxicity. Int J Cancer,1997,72(3)∶431-440.
  • 6[6]Pilch H, Hohn H, Neukirch C, et al. Antigen-driven T-cell selec-tion in patients with cervical cancer as evidenced by T-cell receptor analysis and recognition of autologous tumor. Clin Diagn Lab Immunol,2002,9(2)∶267-278.
  • 7[7]Li Y, Yang L, Chen S, et al. Clonal expansion T cells identified in acute monoblastic leukemia by CDR3 size analysis of TCR V beta repertoire using RT-PCR and genescan. Chin Med J (Engl),2002,115(1)∶69-71.
  • 8[9]Jorgensen JL, Esser U, Fazekas de St Groth B, et al. Mapping T-cell receptor-peptide contacts by variant peptide immunization of single-chain transgenics. Nature,1992,355(6357)∶224-230.
  • 9[10]Weidmann E, Elder EM, Trucco M, et al. Usage of T-cell receptor V beta chain genes in fresh and cultured tumor-infiltrating lymphocytes from human melanoma. Int J Cancer,1993,54(3)∶383-390.
  • 10[11]Halapi E. Oligoclonal T cells in human cancer. Med Oncol,1998,15(4)∶203-211.

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癌症进展
2010年 第1期

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