摘要
目的研究银杏叶提取物（ＥＧＢ）对老龄前期小鼠血液流变学的影响。方法采用毛细管微量法和毛细管微量热沉法分别测定红细胞压积（ＨＣＴ）及纤维蛋白原（Ｆｉｂ），应用全自动血液流变仪测定全血粘度（ηｂ）、红细胞聚集系数（ＶＡＬ）、血栓形成系数（ＴＥＬ）。结果ＥＧＢ（２５，５０，１００ｍｇ·ｋｇ－１，ｉｇ，ｑｄ×２１）可明显降低老龄前期小鼠的ＨＣＴ、Ｆｉｂ，同时可降低ηｂ，缩小ＶＡＬ及ＴＥＬ。结论ＥＧＢ能明显降低老龄前期小鼠血液粘度。
Objective To study the effect of extract the leaves of Ginkgo biloba(EGB) on homorheology in presenium mice. Methods Hemotocrit (HCT) and fibrinogen(Fib) were determined by capillary micromethod and capillary heat microprecipitation method. Measurements of blood viscosity(ηb), intravascular agglutination L.(VAL) and thormbus embolization L.(TEL) were also used. Results EGB(25￣100 mg·kg -1 ,ig, qd×21) markedly reduced HCT and Fib. There were also significant change on ηb, VAL and TEL. Conclusions EGB has a markedly decreaseing effect on blood viscosity and can obviously improve the blood circulation.
出处
《安徽医科大学学报》
CAS
1998年第6期418-419,共2页
Acta Universitatis Medicinalis Anhui
基金
安徽省自然科学基金
关键词
血液流变学
银杏
药理学
小鼠
银杏叶提取物
hemorheology
Ginkgo biloba/pharmacol
plant extracts
mice Free words extract of the leaves of Ginkgo biloba
