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经颅磁刺激运动诱发电位在脊柱脊髓损伤的临床应用研究 被引量:2

Clinical application of TMS MEP in spinal cord injury
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摘要 目的评价经颅磁刺激运动诱发电位(TMSMEP)在脊柱脊髓损伤诊断中的作用。方法测定21例完全性脊髓损伤患者、35例不完全性脊髓损伤患者双侧胫前肌与腓肠肌的TMSMEP,随访6个月~2年,以20例正常成人TMSMEP作对照。结果21例完全性脊髓损伤患者中,19例双侧胫前肌及腓肠肌TMSMEP消失,随访截瘫无恢复;2例圆锥损伤有异常TMSMEP,截瘫及TMSMEP基本恢复。35例不完全性脊髓损伤患者中,每例均可记录到1块以上靶肌的TMSMEP,随访33例,截瘫及TMSMEP均有不同程度的恢复,其中术前25块靶肌肌力0级而有异常TMSMEP,术后肌力除2块无恢复外,其余均有明显恢复或正常。术后TMSMEP的恢复时间和程度均较体检所见早且明显。结论TMSMEP测定对于脊髓损伤的诊断和预后的估计。 Objective To evaluate transcranial magnetic stimulation motor evoked potential (TMS MEP) in the diagnosis of spinal cord injury. Method 56 patients with injury of the spinal cord and cauda equina were examined using TMS MEP and followed up. Result In 21 patients with complete paralysis, TMS MEP of bilateral tibialis anterior and gastrocnemius disappeared and paralysis did not recover. Abnormal was noted TMS MEP and paralysis not recovered in 2 patients with injury of conus medullaris and cauda equina. Incomplete paralysis occurred in 35 patients.TMS MEPs of more than one muscle in every patient were recorded. Paralysis and TMS MEPs recovered in different degree in the 33 patients, in which the strength was 0 class and TMS MEPs were abnormal in 25 target muscles before operation whereas their strength obviously recovered or even normalized after operation except two muscles. Conclusion TMS MEP is an effective method for diagnosis and prognosis of spinal cord injury.
出处 《中华外科杂志》 CAS CSCD 北大核心 1998年第12期714-716,共3页 Chinese Journal of Surgery
基金 广东省重点科技攻关项目
关键词 磁刺激 诱发电位 脊髓损伤 TMS-MEP 脊柱损伤 Evoked potentials Spinal cord injury Clinical studies
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参考文献3

  • 1关骅,中国脊柱脊髓杂志,1997年,7卷,43页
  • 2何爱珊,中国脊柱脊髓杂志,1997年,7卷,105页
  • 3冯远明,中国生物医学工程学报,1995年,14卷,74页

同被引文献22

  • 1谢红雯,刘树山,吴承远,沙成,王大明,王长春,杨玉明,裴傲.急性脊髓损伤时经颅磁刺激运动诱发电位监测的实验研究[J].中华外科杂志,2004,42(13):787-791. 被引量:3
  • 2冯远明,王明时,郭青.脑部磁刺激磁场和感应电场的初步研究[J].中国生物医学工程学报,1995,14(1):74-79. 被引量:8
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  • 9Yamamoto Y,Kawaguchi M,Hayashi H,et al.The effects of the neuromuscular blockade levels on amplitudes of posttetanic motorevoked potentials and movement in response to transcranial stimulation in patients receiving propofol and fentanyl anesthesia.Anesth Analg,2008,106:930-934.
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