摘要
甲状腺相关性眼病（ＴＡＯ）是由一系列甲状腺疾病所致眼部损害。本组２４４例ＴＡＯ的甲状腺疾病以Ｇｒａｖｅｓ（ＧＤ）居首位（９７５３％），其中ＧＤ伴眼病８１１４％，眼型ＧＤ１６３９％。依次是桥本病（１２３％）、甲状腺癌（０８２％）、甲状腺腺瘤（０４２％）。以中青年多发，男女性别差异不大，双眼（９０５７％）发病较单眼多。Ⅲ～Ⅳ级眼病最常见。ＴＡＯ可发生在甲亢前或甲亢后，或甲状腺机能正常，甚至甲状腺机能减退者。肾上腺糖皮质激素与氨甲喋呤联合治疗效果较好。甲亢治疗过度、感染、１３１Ⅰ治疗、甲状腺切除、甲亢复发、用眼过度、精神创伤等。
Thyroid associated ophthalmopathy(TAO)is a kind of eye leisions caused by a series of thyroid diseases.There were 244 case with TAO in the study,among thyroid diseases,Graves’diseases(GD)(97 53%,GD with eye diseases 81 14%,ocular GD 16 39%),Hashimoto diseases(1 23%),thyroid carcinoma(0 82%)and thyroid adenoma(0 42%)were placed respectively.Most patients with TAO were young and mid-aged people.There was no sex difference.Double eyes were more involved than single ones.TAO of Grade Ⅲ～Ⅳ were more common.TAO occured before or after or synchronously the onset of hyperthyroidism,did in euthyroidism,or even in hypothyroidism.Good outcome can be achieved by treating TAO with adrenal corticosteroids combined with MTX.The following factors may induce or deteriorate TAO,such as overdose oral antithyroid drug therapy for hyperthyroidism、infection、 131 I regimen、thyroidectomy、reoccurence of hyperthyroidism、excessive use of eyes、mental stress etc.
出处
《华西医学》
CAS
1998年第4期416-418,共3页
West China Medical Journal
